QuickView for Zfp36 (gene)
- Gene Symbol:
- ZFP36
Homo sapiens - Full name:
- ZFP36 ring finger protein
- Synonyms:
- G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36, mRNA decay activator protein ZFP36, G0/G1 switch regulatory protein 24, growth factor-inducible nuclear protein NUP475, tristetraprolin, tristetraproline, zinc finger protein 36 homolog, zinc finger protein 36, C3H type, homolog, zinc finger protein, C3H type, 36 homolog
- Genomic Location:
- Chr 19: 44589327-44591885
- Orthologs:
- Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Macaca mulatta , Bos taurus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
19q13.2
GO Molecular Function
cytokine binding | kinase binding | RNA polymerase binding | cation binding | 14-3-3 protein binding | protein kinase binding | enzyme binding | nucleic acid binding | mRNA binding | chemokine binding | single-stranded RNA binding | DNA binding | ion binding | AU-rich element binding | organic cyclic compound binding | protein binding | mRNA 3'-UTR AU-rich region binding | mRNA 3'-UTR binding | C-C chemokine binding | heat shock protein binding | metal ion binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | gene silencing by RNA | response to extracellular stimulus | response to nutrient levels | negative regulation of immune system process | response to cytokine | response to lipopolysaccharide | RNA stabilization | regulation of cellular localization | intracellular signal transduction | regulation of localization | regulation of programmed cell death | positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA | establishment of localization | regulation of immune system process | response to hormone | negative regulation of cellular process | mRNA stabilization | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cellular response to tumor necrosis factor | positive regulation of intracellular mRNA localization | negative regulation of translation, ncRNA-mediated | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | cellular process | regulation of gene expression, epigenetic | organic substance catabolic process | cellular response to granulocyte macrophage colony-stimulating factor stimulus | regulation of cytokine biosynthetic process | localization | negative regulation of nucleic acid-templated transcription | macromolecule localization | response to growth factor | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of fat cell differentiation | regulation of cell differentiation | positive regulation of mRNA catabolic process | regulation of mRNA stability | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | gene silencing | regulation of metabolic process | catabolic process | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of gene silencing by miRNA | MAPK cascade | mRNA catabolic process | regulation of keratinocyte proliferation | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay | response to stimulus | negative regulation of erythrocyte differentiation | cellular response to fibroblast growth factor stimulus | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | signal transduction by protein phosphorylation | response to stress | posttranscriptional regulation of gene expression | regulation of cell proliferation | response to starvation | regulation of epithelial cell differentiation | response to molecule of bacterial origin | regulation of gene silencing | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | negative regulation of hemopoiesis | protein modification process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | macromolecule modification | nucleobase-containing compound catabolic process | stress-activated protein kinase signaling cascade | negative regulation of polynucleotide adenylyltransferase activity | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | regulation of interleukin-2 biosynthetic process | response to external biotic stimulus | nitrogen compound metabolic process | 3'-UTR-mediated mRNA destabilization | negative regulation of catalytic activity | phosphorus metabolic process | response to granulocyte macrophage colony-stimulating factor | regulation of catalytic activity | miRNA mediated inhibition of translation | regulation of gene expression | organic substance transport | cellular response to stress | response to lipid | regulation of epidermis development | gene silencing by miRNA | RNA catabolic process | negative regulation of cytokine production | positive regulation of cellular metabolic process | negative regulation of myeloid cell differentiation | regulation of keratinocyte differentiation | regulation of nitrogen compound metabolic process | regulation of RNA stability | response to corticosteroid | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | negative regulation of viral process | nuclear-transcribed mRNA poly(A) tail shortening | cellular response to cytokine stimulus | stress-activated MAPK cascade | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | mRNA transport | phosphorylation | establishment of RNA localization | regulation of epithelial cell apoptotic process | protein phosphorylation | regulation of tumor necrosis factor production | cellular response to corticosteroid stimulus | phosphate-containing compound metabolic process | negative regulation of cytokine biosynthetic process | response to bacterium | mRNA destabilization | posttranscriptional gene silencing | cell communication | regulation of cellular metabolic process | regulation of keratinocyte apoptotic process | regulation of protein metabolic process | aromatic compound catabolic process | negative regulation of interleukin-2 production | regulation of RNA metabolic process | regulation of viral process | 3'-UTR-mediated mRNA stabilization | p38MAPK cascade | negative regulation of mRNA catabolic process | cellular response to epidermal growth factor stimulus | protein metabolic process | posttranscriptional gene silencing by RNA | response to organic substance | negative regulation of interleukin-2 biosynthetic process | regulation of hemopoiesis | response to wounding | cellular macromolecule catabolic process | nucleobase-containing compound transport | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of erythrocyte differentiation | regulation of gene silencing by RNA | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of mRNA catabolic process | negative regulation of cellular protein metabolic process | RNA destabilization | cellular response to steroid hormone stimulus | negative regulation of translation | response to epidermal growth factor | RNA transport | negative regulation of protein metabolic process | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of epithelial cell proliferation | cellular protein metabolic process | regulation of cytokine production | positive regulation of fat cell differentiation | response to biotic stimulus | positive regulation of gene silencing by miRNA | regulation of developmental process | cellular protein modification process | regulation of intracellular mRNA localization | negative regulation of transcription by RNA polymerase II | response to fibroblast growth factor | heterocycle metabolic process | regulation of nuclear-transcribed mRNA poly(A) tail shortening | regulation of viral transcription | positive regulation of metabolic process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | response to steroid hormone | regulation of translation | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | RNA localization | negative regulation of viral transcription | negative regulation of cell differentiation | regulation of epidermal cell differentiation | response to other organism | signal transduction | positive regulation of gene expression | response to glucocorticoid | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cytoplasmic stress granule | exosome (RNase complex) | cell | Dcp1-Dcp2 complex | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | mRNA cap binding complex | RISC-loading complex | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | CCR4-NOT complex | cytosol | intracellular | RNA cap binding complex
