Zinc finger, BED-type QuickView - Correlation Engine

Description:: The BED finger, which was named after the Drosophila proteins BEAF and DREF, isfound in one or more copies in cellular regulatory factors and transposasesfrom plants, animals and fungi. The BED finger is an about 50 to 60 amino acidresidues domain that contains a characteristic motif with two highly conservedaromatic positions, as well as a shared pattern of cysteines and histidinesthat is predicted to form a zinc finger. As diverse BED fingers are able tobind DNA, it has been suggested that DNA-binding is the general function ofthis domain.Some proteins known to contain a BED domain are listed below: Animal, fungal and plant AC1 and Hobo-like transposases. Caenorhabditis elegans protein dpy-20, a predicted cuticular-gene transcriptional regulator. Drosophila BEAF (boundary element-associated factor), which is thought to be involved in chromatin insulation. Drosophila DREF, a transcriptional regulator for S-phase genes. Tobacco 3AF1 and tomato E4/E8-BP1, which are light- and ethylene-regulated DNA binding proteins that contain two BED fingers.

QuickView for Zinc finger, BED-type (biogroup)