QuickView for add1 (gene)

Gene Symbol:

ADD1 Homo sapiens

Full name:

adducin 1

Synonyms:

ADDA, alpha-adducin, adducin 1 (alpha), erythrocyte adducin alpha subunit

Genomic Location:

Chr 4: 2815382-2901587

Description:

Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-ter...

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Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CCCACAT_MIR2993P ,  AML_Q6 ,  TTTGTAG_MIR520D ,  CTTTGTA_MIR524 ,  GGGCGGR_SP1_Q6 ,  ATATGCA_MIR448 ,  GAGCCAG_MIR149 ,  COREBINDINGFACTOR_Q6 ,  GGGTGGRR_PAX4_03

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-299-3p

Cytogenetic Map:

4p16.3

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