QuickView for angiotensin iv receptor (gene)
- Gene Symbol:
- LNPEP
Homo sapiens - Full name:
- leucyl and cystinyl aminopeptidase
- Synonyms:
- CAP, IRAP, P-LAP, PLAP, leucyl-cystinyl aminopeptidase, AT (4) receptor, angiotensin IV receptor, cystinyl aminopeptidase, insulin-regulated aminopeptidase, insulin-regulated membrane aminopeptidase, insulin-responsive aminopeptidase, otase, oxytocinase, placental leucine aminopeptidase, vasopressinase
- Genomic Location:
- Chr 5: 96297102-96390871
- Description:
-
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The pro...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
5q15
GO Molecular Function
metallopeptidase activity | peptide binding | cation binding | hydrolase activity | catalytic activity | exopeptidase activity | amide binding | ion binding | metalloexopeptidase activity | protein binding | zinc ion binding | aminopeptidase activity | metalloaminopeptidase activity | transition metal ion binding | metal ion binding | peptidase activity
GO Biological Process
metallopeptidase activity | SMAD protein signal transduction | antigen processing and presentation | proteolysis | cellular process | organic substance catabolic process | female pregnancy | regulation of cellular process | regulation of metabolic process | catabolic process | response to stimulus | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | protein modification process | macromolecule modification | cell-cell signaling | nitrogen compound metabolic process | reproductive process | negative regulation of cold-induced thermogenesis | antigen processing and presentation of exogenous peptide antigen via MHC class I | protein catabolic process | exopeptidase activity | protein modification by small protein conjugation | enzyme linked receptor protein signaling pathway | cellular amide metabolic process | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | metalloexopeptidase activity | cell communication | transmembrane receptor protein serine/threonine kinase signaling pathway | peptide metabolic process | protein polyubiquitination | antigen processing and presentation of exogenous antigen | aminopeptidase activity | protein metabolic process | protein ubiquitination | peptide catabolic process | antigen processing and presentation of peptide antigen via MHC class I | cell surface receptor signaling pathway | metalloaminopeptidase activity | metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | organonitrogen compound catabolic process | signaling | cellular protein metabolic process | cellular protein modification process | antigen processing and presentation of peptide antigen | immune system process | cellular metabolic process | peptidase activity | signal transduction | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | early endosome lumen | endomembrane system | plasma membrane | vacuole | vesicle | perinuclear region of cytoplasm | lytic vacuole | integral component of plasma membrane | endosome | extracellular region | membrane-bounded organelle | endosome lumen | organelle | vesicle membrane | lysosome | cell periphery | membrane-enclosed lumen | early endosome | cytosol | intracellular vesicle | intracellular | lysosomal membrane | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane | vacuolar membrane
