QuickView for aphakia (gene)
- Gene Symbol:
- Pitx3
Mus musculus - Full name:
- paired-like homeodomain transcription factor 3
- Synonyms:
- Ptx3, ak, pituitary homeobox 3, Pituitary homeobox 3 (Homeobox protein PITX3), aphakia, homeobox protein PITX3
- Genomic Location:
- Chr 19: 46210175-46222815
- Orthologs:
- Homo sapiens , Rattus norvegicus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | brain development | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | positive regulation of apoptotic process | regulation of cell development | regulation of programmed cell death | eye development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | cell differentiation | nervous system development | neurogenesis | generation of neurons | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | negative regulation of gliogenesis | neuron development | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | head development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | midbrain development | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | positive regulation of neuron death | sensory organ development | regulation of cellular metabolic process | eye morphogenesis | regulation of neuron apoptotic process | positive regulation of cell proliferation | regulation of RNA metabolic process | positive regulation of cell proliferation in midbrain | neuron differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | lens morphogenesis in camera-type eye | positive regulation of neuron apoptotic process | anatomical structure development | regulation of neural precursor cell proliferation | metabolic process | regulation of RNA biosynthetic process | behavior | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | positive regulation of programmed cell death | transcription, DNA-templated | dopaminergic neuron differentiation | camera-type eye development | regulation of gliogenesis | regulation of transcription, DNA-templated | cell development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | camera-type eye morphogenesis | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | lens fiber cell differentiation | negative regulation of cell development | negative regulation of cell differentiation | lens development in camera-type eye | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | somatodendritic compartment | cell body | cell | neuronal cell body | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
