QuickView for apoptosome (compound)

Name:	Apoptosomes
Description:	Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.
Synonyms:	Complex, Apoptosomal Protein; Apoptosomal Protein Complex; Apoptosome; Protein Complex, Apoptosomal