Name: | Aristolochic Acids |
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PubChem Substance ID: | 3751105 |
Description: | Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES). |
Synonyms: |
Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 6-nitro-, bis(8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylate); 67123-64-2; Aristolochic acids; CCRIS 52; Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-, 6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylate (2:1)
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