QuickView for atrogin-1 (gene)
- Gene Symbol:
- Fbxo32
Rattus norvegicus - Full name:
- F-box protein 32
- Synonyms:
- Atrogin1, MAFbx, F-box only protein 32, atrogin-1, atrophy gene 1, muscle atrophy F-box protein
- Genomic Location:
- Chr 7: 94909568-94942444
- Description:
-
may act as an SCF-type E3 ubiquitin ligase; plays a role in skeletal atrophy
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | ubiquitin-protein transferase activity | transferase activity
GO Biological Process
regulation of muscle system process | positive regulation of apoptotic process | proteolysis | regulation of programmed cell death | response to hormone | response to dexamethasone | regulation of cardiac muscle cell apoptotic process | response to drug | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | positive regulation of muscle cell apoptotic process | negative regulation of muscle hypertrophy | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | catabolic process | response to muscle inactivity | response to stimulus | cellular response to xenobiotic stimulus | cellular protein catabolic process | cellular response to organic cyclic compound | protein modification process | macromolecule modification | cellular response to hormone stimulus | response to inactivity | nitrogen compound metabolic process | response to denervation involved in regulation of muscle adaptation | response to ketone | response to lipid | protein catabolic process | negative regulation of cardiac muscle hypertrophy | protein modification by small protein conjugation | response to corticosteroid | cellular response to glucocorticoid stimulus | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | cellular response to drug | regulation of muscle cell apoptotic process | protein metabolic process | regulation of cardiac muscle hypertrophy | response to organic substance | protein ubiquitination | response to antineoplastic agent | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | response to electrical stimulus involved in regulation of muscle adaptation | positive regulation of cell death | organic substance metabolic process | muscle atrophy | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | cellular response to steroid hormone stimulus | cellular response to dexamethasone stimulus | ubiquitin-dependent protein catabolic process | positive regulation of cardiac muscle cell apoptotic process | organonitrogen compound catabolic process | response to organic cyclic compound | cellular protein metabolic process | cellular protein modification process | response to electrical stimulus | cellular metabolic process | cellular response to organic substance | regulation of cell death | response to steroid hormone | modification-dependent protein catabolic process | muscle system process | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
supramolecular fiber | intracellular membrane-bounded organelle | catalytic complex | sarcomere | cell | nuclear lumen | myofibril | cytoplasm | intracellular organelle | ubiquitin ligase complex | contractile fiber | protein-containing complex | nucleoplasm | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | I band | membrane-enclosed lumen | SCF ubiquitin ligase complex | Z disc | cytosol | intracellular | supramolecular complex
