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QuickView for basic fibroblast growth factor (gene)


Gene Symbol:
Fgf2 Mus musculus Mus musculus
Full name:
fibroblast growth factor 2
Synonyms:
Fgf-2, Fgfb, bFGF, fibroblast growth factor 2, HBGF-2, basic fibroblast growth factor, heparin-binding growth factor 2
Genomic Location:
Chr 3: 37247772-37303719
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_008006
XM_006535399
Protein Names
Q541T2
P15655



GO Molecular Function

receptor-receptor interaction | protein-containing complex binding | signaling receptor binding | carbohydrate derivative binding | molecular function regulator | anion binding | fibroblast growth factor receptor binding | ion binding | integrin binding | heparin binding | cell adhesion molecule binding | transcription coactivator activity | protein binding | receptor regulator activity | growth factor activity | nuclear receptor transcription coactivator activity | receptor ligand activity | cytokine activity | chemoattractant activity | glycosaminoglycan binding | growth factor receptor binding | transcription coregulator activity

GO Biological Process

positive regulation of smooth muscle cell proliferation | regulation of ERK1 and ERK2 cascade | brain development | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | cell motility | muscle tissue development | calcium ion transmembrane import into cytosol | regulation of cell development | cytosolic calcium ion transport | regulation of localization | morphogenesis of an epithelium | positive regulation of striated muscle tissue development | regulation of programmed cell death | phosphatidylinositol metabolic process | establishment of localization | blood vessel endothelial cell migration | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | regulation of heart growth | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of endothelial cell chemotaxis | respiratory tube development | nervous system development | organ growth | regulation of sprouting angiogenesis | epithelial cell migration | cellular chemical homeostasis | neurogenesis | polyol metabolic process | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | regulation of fibroblast migration | phospholipid metabolic process | blood vessel morphogenesis | regulation of cardiac muscle cell proliferation | positive regulation of vascular smooth muscle cell proliferation | positive regulation of phosphatidylinositol 3-kinase activity | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | metal ion transport | developmental growth | carbohydrate derivative catabolic process | epithelium migration | regulation of skeletal muscle cell proliferation | positive regulation of cell fate specification | renal tubule morphogenesis | regulation of striated muscle tissue development | positive regulation of protein kinase activity | regulation of chemotaxis | glandular epithelial cell differentiation | branching involved in ureteric bud morphogenesis | glycosaminoglycan catabolic process | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | positive regulation of cell division | diencephalon development | regulation of canonical Wnt signaling pathway | establishment of localization in cell | tissue development | regulation of cell differentiation | negative regulation of cell motility | negative regulation of wound healing | regulation of angiogenesis | regulation of protein kinase B signaling | regulation of cellular process | regulation of osteoblast differentiation | regulation of metabolic process | gliogenesis | pituitary gland development | catabolic process | regulation of cytosolic calcium ion concentration | regulation of skeletal muscle satellite cell proliferation | positive regulation of cellular protein metabolic process | epithelium development | coronary vasculature morphogenesis | cellular lipid metabolic process | calcium ion homeostasis | regulation of cell division | urogenital system development | positive regulation of epithelial cell migration | nephron tubule morphogenesis | head development | sprouting angiogenesis | calcium ion transport into cytosol | regulation of vasculature development | response to stimulus | positive regulation of vascular endothelial cell proliferation | vasculature development | respiratory system development | cellular response to fibroblast growth factor stimulus | positive regulation of protein metabolic process | carboxylic acid catabolic process | response to stress | endothelial cell migration | alcohol metabolic process | regulation of cell proliferation | cardiac muscle cell proliferation | tube morphogenesis | cardiac muscle tissue development | cellular localization | divalent metal ion transport | cardiovascular system development | positive regulation of sprouting angiogenesis | midbrain development | positive regulation of lipase activity | positive regulation of blood vessel endothelial cell migration | positive regulation of endothelial cell chemotaxis to fibroblast growth factor | regulation of endothelial cell chemotaxis to fibroblast growth factor | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | regulation of wound healing | cartilage development | cellular biosynthetic process | kidney development | embryo development | regulation of phosphatidylinositol 3-kinase activity | heart growth | adenohypophysis development | activation of protein kinase activity | molecular function regulator | growth factor dependent regulation of skeletal muscle satellite cell proliferation | positive chemotaxis | metal ion homeostasis | blood vessel development | regulation of nucleic acid-templated transcription | locomotion | organic hydroxy compound metabolic process | positive regulation of phospholipase C activity | system development | nitrogen compound metabolic process | regulation of signal transduction | ureteric bud development | multicellular organism development | cell migration | calcium ion transmembrane transport | regulation of MAPK cascade | phosphorus metabolic process | mammary gland development | neuroepithelial cell differentiation | positive regulation of muscle organ development | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | kidney morphogenesis | fibroblast growth factor receptor signaling pathway | ion transmembrane transport | hyaluronan metabolic process | regulation of ossification | wound healing | regulation of gene expression | regulation of retinal cell programmed cell death | positive regulation of chemotaxis | regulation of cell fate specification | kidney epithelium development | organophosphate metabolic process | coronary vasculature development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to axon injury | animal organ morphogenesis | phospholipid biosynthetic process | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | small molecule metabolic process | positive regulation of intracellular signal transduction | substantia nigra development | regulation of cellular component movement | regulation of transcription by RNA polymerase II | regulation of cell migration involved in sprouting angiogenesis | negative regulation of fibroblast migration | positive regulation of hydrolase activity | positive regulation of cell differentiation | regulation of endothelial cell migration | stem cell differentiation | positive regulation of cell migration | cell proliferation | negative regulation of epithelial cell migration | biosynthetic process | positive regulation of cardiac muscle cell proliferation | negative regulation of sequestering of calcium ion | regulation of cellular protein metabolic process | glial cell differentiation | positive regulation of ossification | angiogenesis | angiogenesis involved in coronary vascular morphogenesis | mesonephric epithelium development | lipid biosynthetic process | regulation of phospholipase activity | endocrine system development | mesonephros development | cation homeostasis | phosphate-containing compound metabolic process | negative regulation of response to wounding | regulation of lipid kinase activity | chondroblast differentiation | negative regulation of blood vessel endothelial cell migration | striated muscle tissue development | cellular cation homeostasis | cell communication | corticotropin hormone secreting cell differentiation | regulation of cellular metabolic process | regulation of protein kinase activity | renal tubule development | positive regulation of DNA biosynthetic process | activation of MAPKK activity | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | neuroendocrine cell differentiation | regulation of locomotion | embryo development ending in birth or egg hatching | glycerolipid metabolic process | transcription coactivator activity | regulation of RNA metabolic process | renal system development | regulation of phospholipid metabolic process | regulation of cellular response to growth factor stimulus | nephron development | cardiac muscle tissue growth | carboxylic acid metabolic process | regulation of phospholipase C activity | positive regulation of molecular function | release of sequestered calcium ion into cytosol | positive regulation of osteoblast differentiation | cation transmembrane transport | regulation of signaling receptor activity | receptor regulator activity | ureteric bud morphogenesis | positive regulation of organ growth | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | regulation of cardiac muscle tissue development | tissue morphogenesis | glycerophospholipid biosynthetic process | branching morphogenesis of an epithelial tube | regulation of kinase activity | response to wounding | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | regulation of neural precursor cell proliferation | metabolic process | regulation of RNA biosynthetic process | nuclear receptor transcription coactivator activity | chemical homeostasis | calcium ion transport | receptor ligand activity | cytokine activity | organic substance metabolic process | regulation of sequestering of calcium ion | connective tissue development | chemoattractant activity | nephron morphogenesis | animal organ development | regulation of endothelial cell proliferation | forebrain development | negative regulation of cellular component movement | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | ion homeostasis | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | inorganic cation transmembrane transport | mammary gland epithelium development | phosphatidylinositol biosynthetic process | positive regulation of muscle tissue development | positive regulation of phospholipase activity | positive regulation of endothelial cell migration | positive regulation of MAPK cascade | lung development | stem cell development | morphogenesis of a branching epithelium | positive regulation of canonical Wnt signaling pathway | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | regulation of animal organ formation | organonitrogen compound catabolic process | regulation of response to wounding | regulation of cell communication | regulation of blood vessel endothelial cell migration | muscle cell proliferation | transmembrane transport | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | thyroid-stimulating hormone-secreting cell differentiation | cell development | positive regulation of cell migration involved in sprouting angiogenesis | regulation of developmental growth | regulation of epithelial cell proliferation | organic acid metabolic process | positive regulation of phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | cation transport | positive regulation of MAP kinase activity | regulation of organ growth | regulation of cerebellar granule cell precursor proliferation | regulation of nervous system development | regulation of developmental process | glycerophospholipid metabolic process | positive regulation of neural precursor cell proliferation | positive regulation of DNA metabolic process | developmental process | regulation of DNA biosynthetic process | tube development | carbohydrate derivative metabolic process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | cell migration involved in sprouting angiogenesis | response to fibroblast growth factor | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | negative regulation of endothelial cell migration | positive regulation of lipid kinase activity | transcription coregulator activity | cellular metal ion homeostasis | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | positive regulation of cell fate commitment | mammary gland epithelial cell differentiation | regulation of cell fate commitment | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | organ induction | positive regulation of lipid metabolic process | ion transport | positive regulation of cerebellar granule cell precursor proliferation | skeletal system development | positive regulation of Wnt signaling pathway | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | positive regulation of cell motility | negative regulation of cell death | developmental induction | circulatory system development | chemotaxis | divalent inorganic cation homeostasis | negative regulation of locomotion | positive regulation of angiogenesis | nephron tubule development | inositol phosphate biosynthetic process | positive regulation of signaling | neural nucleus development | inositol phosphate metabolic process | signal transduction | regulation of signaling | mesonephric tubule development | hyaluronan catabolic process | positive regulation of gene expression | cellular response to growth factor stimulus | glycosaminoglycan metabolic process | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | intracellular