QuickView for bid (gene)

Gene Symbol:

BID Homo sapiens

Full name:

BH3 interacting domain death agonist

Synonyms:

FP497, BH3-interacting domain death agonist, BID isoform ES(1b), BID isoform L(2), BID isoform Si6, Human BID coding sequence, apoptic death agonist, desmocollin type 4, p22 BID

Genomic Location:

Chr 22: 16596906-16637258

Description:

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it t...

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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

22q11.21

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