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Name: BRCA2 Protein
Description: A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
Synonyms:
Fanconi Anemia Complementation Group D1 Protein; Fanconi Anemia Group D1 Protein; FANCD1 Protein; BRCA2 Gene Product; Fanconi Anemia Group D1 Complementing Protein; Breast Cancer 2 Gene Product; Breast Cancer 2 Protein