QuickView for c-Jun (gene)
- Gene Symbol:
- Jun
Mus musculus - Full name:
- jun proto-oncogene
- Synonyms:
- AP-1, Junc, c-jun, transcription factor AP-1, AH119, AP1, Jun oncogene, V-jun avian sarcoma virus 17 oncogene homolog, activator protein 1, immediate early, jun A, proto-oncogene c-jun
- Genomic Location:
- Chr 4: 94715746-94718878
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-139 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-30-3p , Predicted Gene Targets for miR-362 , Predicted Gene Targets for miR-409-3p , Predicted Gene Targets for miR-493-5p , Predicted Gene Targets for miR-495
GO Molecular Function
sequence-specific DNA binding | enzyme activator activity | transcription regulatory region DNA binding | HMG box domain binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | GTPase activator activity | proximal promoter sequence-specific DNA binding | enzyme binding | RNA polymerase II activating transcription factor binding | nucleic acid binding | GTPase regulator activity | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function regulator | chromatin binding | protein domain specific binding | ubiquitin-like protein ligase binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | ubiquitin protein ligase binding | RNA polymerase II transcription factor binding | activating transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | cAMP response element binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | enzyme regulator activity | transcription coregulator activity | SMAD binding | heterocyclic compound binding | R-SMAD binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | SMAD protein signal transduction | response to radiation | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to nutrient levels | regulation of monocyte differentiation | response to endoplasmic reticulum stress | release of cytochrome c from mitochondria | response to cytokine | positive regulation of cellular component organization | response to lipopolysaccharide | intracellular signal transduction | enzyme activator activity | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | eye development | regulation of immune system process | response to hormone | myeloid cell differentiation | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | response to metal ion | cell differentiation | positive regulation of epithelial cell proliferation | positive regulation of fibroblast proliferation | nervous system development | cellular response to extracellular stimulus | response to drug | negative regulation of protein phosphorylation | neurogenesis | positive regulation of phosphate metabolic process | regulation of DNA replication | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | generation of neurons | interaction with symbiont | blood vessel morphogenesis | positive regulation of vascular smooth muscle cell proliferation | regulation of neuron death | positive regulation of GTPase activity | cellular response to potassium ion starvation | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | heart morphogenesis | neuron development | immune system development | negative regulation of nucleic acid-templated transcription | GTPase activator activity | learning | negative regulation of apoptotic process | cellular response to starvation | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | interspecies interaction between organisms | regeneration | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | positive regulation by host of viral transcription | regulation of protein complex assembly | hepaticobiliary system development | small GTPase mediated signal transduction | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | negative regulation of protein autophosphorylation | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | response to transforming growth factor beta | cellular response to metal ion | positive regulation of epithelial cell migration | response to stimulus | vasculature development | positive regulation of immune system process | positive regulation of protein metabolic process | GTPase regulator activity | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | response to muscle stretch | response to starvation | programmed cell death | cellular response to inorganic substance | cardiovascular system development | cellular response to cadmium ion | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | regulation of DNA binding | apoptotic mitochondrial changes | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular biosynthetic process | mitochondrion organization | molecular function regulator | blood vessel development | regulation of nucleic acid-templated transcription | regulation of membrane potential | leukocyte differentiation | response to nitrogen compound | negative regulation of neuron apoptotic process | apoptotic process | cellular response to hormone stimulus | response to external biotic stimulus | system development | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | positive regulation of viral process | multicellular organism development | positive regulation of DNA replication | regulation of MAPK cascade | response to purine-containing compound | learning or memory | negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | regulation of catalytic activity | cellular response to oxidative stress | regulation of phosphorylation | monocyte differentiation | regulation of gene expression | axon development | outflow tract morphogenesis | cellular response to stress | response to lipid | nervous system process | regulation of protein autophosphorylation | myeloid leukocyte differentiation | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | eyelid development in camera-type eye | response to axon injury | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | liver development | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | negative regulation of DNA binding | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of monocyte differentiation | response to oxidative stress | negative regulation of binding | positive regulation of hydrolase activity | positive regulation of cell differentiation | negative regulation of viral process | positive regulation of myeloid cell differentiation | cognition | positive regulation of cell migration | biosynthetic process | response to cadmium ion | neuron projection regeneration | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | angiogenesis | positive regulation of pri-miRNA transcription by RNA polymerase II | positive regulation of neuron death | regulation of GTPase activity | microglial cell activation | sensory organ development | response to bacterium | negative regulation by host of viral transcription | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | transcription coactivator activity | regulation of RNA metabolic process | regulation of viral process | apoptotic signaling pathway | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | neuron differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | regulation of fibroblast proliferation | DNA-binding transcription factor activity | positive regulation of protein modification process | cellular response to calcium ion | response to organic substance | gland development | regulation of hemopoiesis | response to wounding | response to mechanical stimulus | positive regulation of viral transcription | leading edge cell differentiation | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of DNA-templated transcription in response to stress | positive regulation of DNA-templated transcription, initiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | behavior | positive regulation of cell death | membrane depolarization | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | macrophage activation | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | response to reactive oxygen species | regulation of endothelial cell proliferation | negative regulation of cellular protein metabolic process | gene expression | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | negative regulation of transcription from RNA polymerase II promoter in response to stress | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of phosphate metabolic process | transcription, DNA-templated | response to cAMP | cell activation | positive regulation of MAPK cascade | camera-type eye development | modulation by host of viral transcription | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of epithelial cell migration | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | enzyme regulator activity | regulation of transcription from RNA polymerase II promoter in response to stress | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | response to biotic stimulus | axon regeneration | regulation of developmental process | positive regulation of DNA metabolic process | developmental process | organelle organization | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | Ras protein signal transduction | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | transcription coregulator activity | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to calcium ion | regulation of viral transcription | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | negative regulation of cell death | circulatory system development | negative regulation of viral transcription | regulation of cellular component organization | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
nuclear euchromatin | nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | euchromatin | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | transcription factor AP-1 complex | cytosol | intracellular
