QuickView for cGAS (gene)
- Gene Symbol:
- CGAS
Homo sapiens - Full name:
- cyclic GMP-AMP synthase
- Synonyms:
- C6orf150, MB21D1, h-cGAS, cyclic GMP-AMP synthase, 2'3'-cGAMP synthase, Mab-21 domain containing 1, cGAMP synthase, mab-21 domain-containing protein 1, protein MB21D1
- Genomic Location:
- Chr 6: 74191577-74218764
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
6q13
GO Molecular Function
guanyl ribonucleotide binding | ribonucleoside binding | cation binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | nucleotidyltransferase activity | catalytic activity | chromatin binding | ATP binding | anion binding | adenyl nucleotide binding | DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | double-stranded DNA binding | transferase activity, transferring phosphorus-containing groups | GTP binding | cyclic-GMP-AMP synthase activity | transferase activity | nucleoside binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding
GO Biological Process
positive regulation of immune response | response to virus | positive regulation of cell aging | cyclic nucleotide biosynthetic process | regulation of cell aging | defense response to other organism | regulation of immune system process | positive regulation of developmental process | defense response | cellular process | response to exogenous dsRNA | nucleotide metabolic process | positive regulation of defense response to virus by host | regulation of defense response to virus | regulation of immune response | regulation of cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of type I interferon production | response to stimulus | positive regulation of innate immune response | positive regulation of immune system process | response to stress | cellular nitrogen compound biosynthetic process | activation of innate immune response | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | cellular biosynthetic process | cell-cell signaling | nucleotide biosynthetic process | regulation of cellular response to stress | response to nitrogen compound | response to external biotic stimulus | nitrogen compound metabolic process | phosphorus metabolic process | response to dsRNA | cellular response to DNA damage stimulus | cyclic nucleotide metabolic process | cellular response to stress | organophosphate metabolic process | defense response to virus | cellular response to exogenous dsRNA | small molecule metabolic process | paracrine signaling | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | phosphate-containing compound metabolic process | cell communication | cellular response to dsRNA | activation of immune response | response to organic substance | regulation of innate immune response | metabolic process | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | positive regulation of cytokine production | signaling | response to organic cyclic compound | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | positive regulation of cellular senescence | innate immune response | regulation of defense response to virus by host | heterocycle metabolic process | immune system process | cellular metabolic process | cellular response to organic substance | positive regulation of type I interferon production | response to other organism | regulation of cellular senescence
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
