QuickView for calpain 1 (gene)

Gene Symbol:

CAPN1 Homo sapiens

Full name:

calpain 1

Synonyms:

CANP, CANP1, CANPL1, SPG76, muCANP, muCL, calpain-1 catalytic subunit, CANP 1, calcium-activated neutral proteinase 1, calpain 1, (mu/I) large subunit, calpain mu-type, calpain, large polypeptide L1, calpain-1 large subunit, cell proliferation-inducing gene 30 protein, cell proliferation-inducing protein 30, micromolar-calpain

Genomic Location:

Chr 11: 64705919-64736052

Description:

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes...

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The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  GATA3_01 ,  GATA_Q6 ,  AMEF2_Q6 ,  GATAAGR_GATA_C ,  GATA1_04 ,  TFIII_Q6 ,  CAGGTA_AREB6_01 ,  MEF2_01 ,  LMO2COM_02 ,  GATA1_02 ,  HMEF2_Q6 ,  GTGCCTT_MIR506 ,  AAAYRNCTG_UNKNOWN ,  GATA4_Q3 ,  MMEF2_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a

Cytogenetic Map:

11q13.1

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