QuickView for camel (gene)

Gene Symbol:

CTAG2 Homo sapiens

Full name:

cancer/testis antigen 2

Synonyms:

CAMEL, CT2, CT6.2, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE2B, cancer/testis antigen 2, CTL-recognized antigen on melanoma, LAGE-1a protein, autoimmunogenic cancer/testis antigen NY-ESO-2, cancer/testis antigen 6.2, cancer/testis antigen family 6, member 2a, cancer/testis antigen family 6, member 2b, l antigen family member 1

Genomic Location:

Chr X: 153533445-153535036

Description:

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene h...

View Full Description

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.

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Orthologs:

Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  DR1_Q3

Cytogenetic Map:

Xq28

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