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QuickView for catalase (gene)


Gene Symbol:
CAT Homo sapiens Homo sapiens
Full name:
catalase
Synonyms:
catalase
Genomic Location:
Chr 11: 34417054-34450183
Description:
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stre...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Canis lupus familiaris Pan troglodytes Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11p13


Transcripts Names
NM_001752



GO Molecular Function

NADP binding | cofactor binding | peroxidase activity | cation binding | antioxidant activity | enzyme binding | nucleotide binding | coenzyme binding | signaling receptor binding | hydrolase activity | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | aminoacylase activity | identical protein binding | ion binding | organic cyclic compound binding | tetrapyrrole binding | protein binding | protein homodimerization activity | catalase activity | protein dimerization activity | heme binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | oxidoreductase activity, acting on peroxide as acceptor | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

response to extracellular stimulus | protein homooligomerization | response to radiation | response to nutrient levels | peroxisome organization | exocytosis | neutrophil activation | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | establishment of localization | response to hormone | negative regulation of cellular process | peroxidase activity | response to metal ion | cell differentiation | hydrogen peroxide catabolic process | response to drug | reactive oxygen species metabolic process | generation of precursor metabolites and energy | aerobic respiration | response to antibiotic | intracellular transport | sterol metabolic process | cellular process | secretion | leukocyte degranulation | localization | cellular detoxification | protein transport | antioxidant activity | protein targeting to peroxisome | response to estradiol | triglyceride metabolic process | cellular respiration | macromolecule localization | negative regulation of apoptotic process | response to hypoxia | response to growth factor | positive regulation of cell division | response to inorganic substance | establishment of localization in cell | response to peptide hormone | tissue development | response to hydrogen peroxide | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | epithelium development | cellular component organization | cellular lipid metabolic process | regulation of cell division | urogenital system development | response to UV | response to stimulus | neutrophil degranulation | positive regulation of phosphatidylinositol 3-kinase signaling | response to light intensity | response to stress | intracellular protein transport | leukocyte activation involved in immune response | response to ozone | alcohol metabolic process | response to peptide | cellular localization | secretion by cell | response to alcohol | cellular response to toxic substance | cofactor metabolic process | cellular component assembly | kidney development | drug catabolic process | response to ethanol | response to phenylpropanoid | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | organic hydroxy compound metabolic process | response to nitrogen compound | response to light stimulus | response to inactivity | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | ureteric bud development | multicellular organism development | response to activity | antibiotic metabolic process | response to fatty acid | response to vitamin E | protein complex oligomerization | leukocyte mediated immunity | lipid metabolic process | cellular response to oxidative stress | regulation of gene expression | kidney epithelium development | organic substance transport | cellular response to stress | response to lipid | regulation of nitrogen compound metabolic process | small molecule metabolic process | UV protection | peptide transport | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | vesicle-mediated transport | protein homotetramerization | response to nutrient | response to oxidative stress | protein localization to organelle | response to cadmium ion | response to hyperoxia | mesonephric epithelium development | regulated exocytosis | response to vitamin A | protein tetramerization | response to toxic substance | establishment of protein localization to peroxisome | mesonephros development | regulation of cellular metabolic process | cell activation involved in immune response | myeloid cell activation involved in immune response | positive regulation of signal transduction | neutrophil activation involved in immune response | response to monosaccharide | glycerolipid metabolic process | regulation of RNA metabolic process | renal system development | drug metabolic process | positive regulation of molecular function | catalase activity | protein-containing complex assembly | protein metabolic process | response to organic substance | neutral lipid metabolic process | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | establishment of protein localization to organelle | response to insulin | anatomical structure development | metabolic process | cellular oxidant detoxification | regulation of RNA biosynthetic process | cholesterol metabolic process | oxidation-reduction process | negative regulation of programmed cell death | cellular protein localization | amide transport | immune response | organic substance metabolic process | response to vitamin | animal organ development | response to reactive oxygen species | positive regulation of NF-kappaB transcription factor activity | response to L-ascorbic acid | establishment of protein localization | cell activation | steroid metabolic process | regulation of cell communication | negative regulation of molecular function | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | cellular macromolecule localization | energy derivation by oxidation of organic compounds | developmental process | organelle organization | tube development | hemoglobin metabolic process | detoxification | neutrophil mediated immunity | response to organonitrogen compound | response to lead ion | oxidoreductase activity, acting on peroxide as acceptor | hydrogen peroxide metabolic process | ossification | protein targeting | osteoblast differentiation | immune system process | cellular metabolic process | cellular response to organic substance | regulation of cell death | response to carbohydrate | oxidoreductase activity | negative regulation of cell death | acylglycerol metabolic process | aging | positive regulation of signaling | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | mesonephric tubule development | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

secretory granule | peroxisomal membrane | peroxisomal matrix | mitochondrial intermembrane space | intracellular membrane-bounded organelle | adherens junction | organelle membrane | peroxisome | focal adhesion | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | cell-substrate junction | intracellular organelle | endoplasmic reticulum | ficolin-1-rich granule lumen | Golgi apparatus | secretory vesicle | endomembrane system | plasma membrane | vacuole | vesicle | extracellular exosome | mitochondrion | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | mitochondrial envelope | lysosome | extracellular space | cell periphery | membrane-enclosed lumen | cell-substrate adherens junction | secretory granule lumen | cytosol | intracellular vesicle | intracellular | cell junction | membrane | vesicle lumen