Name: | Antigens, CD3 |
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Description: | Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA). |
Synonyms: |
CD3 Antigens; CD3 Antigen; T3 Antigen; CD3 Complex; Antigen, CD3; T3 Antigens; Antigen, T3; Antigens, T3; T3 Complex
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