QuickView for ceruloplasmin (gene)

Gene Symbol:

CP Homo sapiens

Full name:

ceruloplasmin

Synonyms:

CP-2, ceruloplasmin, ceruloplasmin (ferroxidase)

Genomic Location:

Chr 3: 150373220-150422519

Description:

The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcr...

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The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus ,  Gallus gallus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF3ALPHA_Q6 ,  TATAAA_TATA_01 ,  CEBPB_02 ,  TGTYNNNNNRGCARM_UNKNOWN ,  PAX_Q6 ,  AACTTT_UNKNOWN

Cytogenetic Map:

3q24-q25.1

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