QuickView for chapsyn-110 (gene)

Gene Symbol:

DLG2 Homo sapiens

Full name:

discs large MAGUK scaffold protein 2

Synonyms:

PPP1R58, PSD-93, PSD93, chapsyn-110, disks large homolog 2, DLG2 protein isoform, channel-associated protein of synapse-110, channel-associated protein of synapses, 110kDa, discs, large homolog 2, chapsyn-110, postsynaptic density protein PSD-93, protein phosphatase 1, regulatory subunit 58

Genomic Location:

Chr 11: 82843701-84312113

Description:

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding diff...

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This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  POU6F1_01 ,  FREAC7_01 ,  SMTTTTGT_UNKNOWN ,  OCT1_B ,  GATA1_01 ,  AAGCCAT_MIR135A_MIR135B ,  ACACTCC_MIR122A ,  TTANTCA_UNKNOWN ,  OCT1_04 ,  AREB6_02 ,  P53_DECAMER_Q2 ,  RSRFC4_01 ,  HFH3_01 ,  HOXA4_Q2 ,  PR_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  YTATTTTNR_MEF2_02 ,  CATTGTYY_SOX9_B1 ,  NKX3A_01 ,  GCANCTGNY_MYOD_Q6 ,  AAANWWTGC_UNKNOWN ,  HFH1_01 ,  EVI1_04 ,  RSRFC4_Q2 ,  CEBP_Q2_01 ,  YATTNATC_UNKNOWN ,  HP1SITEFACTOR_Q6 ,  VDR_Q6 ,  LYF1_01 ,  ARP1_01 ,  AREB6_04 ,  WGTTNNNNNAAA_UNKNOWN ,  SRY_01 ,  ATGTACA_MIR493 ,  AMEF2_Q6 ,  FAC1_01 ,  SREBP1_Q6 ,  CTTTGA_LEF1_Q2 ,  IRF1_Q6 ,  GR_Q6_01 ,  NKX22_01 ,  PBX1_01 ,  CTAWWWATA_RSRFC4_Q2 ,  OCT1_Q5_01 ,  OCT_C ,  TGACCTY_ERR1_Q2 ,  HEB_Q6 ,  COMP1_01 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  MEF2_02 ,  TATAAA_TATA_01 ,  CDPCR3HD_01 ,  OCT1_Q6 ,  CEBPB_01 ,  LEF1_Q2 ,  DBP_Q6 ,  TTGGAGA_MIR5155P_MIR519E ,  CAGGTA_AREB6_01 ,  TEF1_Q6 ,  NFY_Q6_01 ,  CEBP_01 ,  CDX2_Q5 ,  CAGGTG_E12_Q6 ,  AP4_01 ,  GR_Q6 ,  TST1_01 ,  NKX62_Q2 ,  GGCNKCCATNK_UNKNOWN ,  SRF_Q4 ,  ACTGAAA_MIR30A3P_MIR30E3P ,  RAAGNYNNCTTY_UNKNOWN ,  CTTTAAR_UNKNOWN ,  TGCCAAR_NF1_Q6 ,  SPZ1_01 ,  TGTTTGY_HNF3_Q6 ,  SOX5_01 ,  PAX8_B ,  OCT1_06 ,  YCATTAA_UNKNOWN ,  AREB6_03 ,  RNGTGGGC_UNKNOWN ,  GFI1_01 ,  NCX_01 ,  AATGTGA_MIR23A_MIR23B ,  EN1_01 ,  OCT1_02 ,  CEBP_Q3 ,  MTF1_Q4 ,  CHX10_01 ,  ELK1_01 ,  TTGTTT_FOXO4_01 ,  AP4_Q6_01 ,  ATF1_Q6 ,  CEBP_C ,  CART1_01 ,  PIT1_Q6 ,  GATA4_Q3 ,  MSX1_01 ,  WWTAAGGC_UNKNOWN ,  MEF2_03 ,  TEF_Q6 ,  SREBP_Q3 ,  CTGCAGY_UNKNOWN ,  PAX_Q6 ,  KMCATNNWGGA_UNKNOWN ,  ICSBP_Q6 ,  TBP_01 ,  PAX3_B ,  ER_Q6_01 ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  CDC5_01 ,  SRY_02 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  ERR1_Q2 ,  ER_Q6 ,  DR4_Q2 ,  TCF1P_Q6 ,  ATGAAGG_MIR205 ,  PPARA_02 ,  CEBPGAMMA_Q6 ,  AAGTCCA_MIR422B_MIR422A ,  GGGTGGRR_PAX4_03 ,  AAGCACA_MIR218 ,  LMO2COM_01 ,  TCF11_01 ,  LBP1_Q6 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

11q14.1

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