Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for choline (compound)


PubChem
Name: Choline
PubChem Compound ID: 10198924
Description: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Molecular formula: C9H19NO7
Molecular weight: 253.25 g/mol
DrugBank
Identification
Name: Choline
Name (isomeric): DB00122
Drug Type: small molecule
Description: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Synonyms:
Bilineurine; Choline ion; (2-Hydroxyethyl)trimethylammonium; 2-Hydroxy-N,N,N-trimethylethanaminium; Cholinum; Choline cation
Category: Lipotropic Agents, Nootropic Agents, Micronutrient, Dietary supplement
CAS number: 62-49-7
Pharmacology
Indication: For nutritional supplementation, also for treating dietary shortage or imbalance
Pharmacology:
This compound is needed for good nerve conduction throughout the CNS (central nervous system) as it is a precursor to acetylcholine (ACh). Choline is also needed for gallbladder regulation, liver function and lecithin (a key lipid) formation. Choline also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Choli...
show more »
Mechanism of Action:
Choline is a major part of the polar head group of phosphatidylcholine. Phosphatidylcholine's role in the maintenance of cell membrane integrity is vital to all of the basic biological processes: information flow, intracellular communication and bioenergetics. Inadequate choline intake would negatively affect all these processes. Choline is also a ...
show more »
Toxicity: Oral rat LD50: 3400 mg/kg
Affected organisms: Humans and other mammals

Targets


Enzymes


Transporters