QuickView for claudin 15 (gene)

Gene Symbol:

CLDN15 Homo sapiens

Full name:

claudin 15

Synonyms:

claudin-15

Genomic Location:

Chr 7: 100662094-100667836

Description:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintain...

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  AP1_C ,  TGANTCA_AP1_C ,  VDR_Q3 ,  GCANCTGNY_MYOD_Q6 ,  ARP1_01 ,  CTTTGA_LEF1_Q2 ,  TTF1_Q6 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  HNF4_Q6 ,  GGGCGGR_SP1_Q6 ,  AP1_Q2_01 ,  CCCNNGGGAR_OLF1_01 ,  NRF2_Q4 ,  AP4_Q6_01 ,  COUP_DR1_Q6 ,  CAGCTG_AP4_Q5 ,  MZF1_02 ,  PPAR_DR1_Q2 ,  TGASTMAGC_NFE2_01

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Cytogenetic Map:

7q22.1

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