QuickView for claudin 5 (gene)

Gene Symbol:

CLDN5 Homo sapiens

Full name:

claudin 5

Synonyms:

AWAL, BEC1, CPETRL1, TMVCF, claudin-5, TMDVCF, transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome

Genomic Location:

Chr 22: 17890550-17892860

Description:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found i...

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  RYTTCCTG_ETS2_B ,  HEN1_01 ,  SYATTGTG_UNKNOWN ,  SREBP1_Q6 ,  STAT1_03 ,  NFKAPPAB65_01 ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  AP2_Q6_01 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  STAT3_01 ,  TTGTTT_FOXO4_01 ,  AAAYRNCTG_UNKNOWN ,  SCGGAAGY_ELK1_02 ,  CREL_01 ,  ELK1_02

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Cytogenetic Map:

22q11.21

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