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QuickView for complement c1s (compound)
| Name: | Complement C1s |
|---|---|
| Description: | A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE). |
| Synonyms: |
Complement 1s; C1s Complement; Complement 1 Esterase; Esterase, Complement 1; Esterase, C 1; C1s, Complement; Complement, C1s; C1 Esterase; C 1 Esterase; Complement Component 1s.
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