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QuickView for contactin 2 (gene)


Gene Symbol:
CNTN2 Homo sapiens Homo sapiens
Full name:
contactin 2
Synonyms:
AXT, FAME5, TAG-1, TAX, TAX1, contactin-2, axonal glycoprotein TAG-1, axonin-1 cell adhesion molecule, contactin 2 (axonal), contactin 2 (transiently expressed), transient axonal glycoprotein 1
Genomic Location:
Chr 1: 203278963-203313761
Description:
This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be a...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q32.1





GO Molecular Function

protein self-association | cell-cell adhesion mediator activity | identical protein binding | carbohydrate binding | protein binding | cell adhesion mediator activity

GO Biological Process

brain development | regulation of axon diameter | cell morphogenesis | regulation of cell projection size | neuronal ion channel clustering | establishment of protein localization to juxtaparanode region of axon | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cell development | establishment of localization | neuron migration | negative regulation of cellular process | microtubule cytoskeleton organization | cell differentiation | protein localization to axon | nervous system development | cell part morphogenesis | clustering of voltage-gated potassium channels | neurogenesis | generation of neurons | membrane organization | microtubule-based process | cellular process | localization | axon ensheathment | cell projection morphogenesis | cell maturation | forebrain cell migration | cerebral cortex GABAergic interneuron differentiation | neuron development | walking behavior | regulation of neuronal synaptic plasticity | central nervous system neuron differentiation | cerebral cortex neuron differentiation | learning | macromolecule localization | axon guidance | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | regulation of neuron projection development | central nervous system myelination | regulation of cell differentiation | cell recognition | regulation of cellular process | regulation of metabolic process | gliogenesis | cell-cell adhesion mediator activity | positive regulation of cellular protein metabolic process | cellular component organization | head development | positive regulation of protein processing | response to stimulus | cell morphogenesis involved in neuron differentiation | oligodendrocyte development | positive regulation of protein metabolic process | neuron projection guidance | ensheathment of neurons | telencephalon cell migration | axon ensheathment in central nervous system | cellular localization | dendrite self-avoidance | positive regulation of proteolysis | regulation of cellular component size | regulation of protein processing | modulation of chemical synaptic transmission | GABAergic neuron differentiation | locomotion | central nervous system neuron development | system development | regulation of signal transduction | myelination | multicellular organism development | cell migration | learning or memory | regulation of axonogenesis | forebrain neuron development | telencephalon development | cerebral cortex GABAergic interneuron development | regulation of neuron differentiation | regulation of gene expression | axon development | nervous system process | neuron recognition | adult walking behavior | positive regulation of cellular metabolic process | adult locomotory behavior | regulation of nitrogen compound metabolic process | vesicle-mediated transport | axonal fasciculation | synapse organization | axonogenesis | cerebral cortex GABAergic interneuron migration | cognition | locomotory behavior | regulation of cellular protein metabolic process | glial cell differentiation | cell morphogenesis involved in differentiation | regulation of cellular metabolic process | presynaptic membrane organization | receptor internalization | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of adenosine receptor signaling pathway | neuron projection fasciculation | neuron maturation | neuron differentiation | regulation of cell morphogenesis involved in differentiation | import into cell | anatomical structure development | cell projection organization | metabolic process | developmental maturation | cellular protein localization | oligodendrocyte differentiation | forebrain generation of neurons | endocytosis | behavior | cell adhesion | neuron projection development | organic substance metabolic process | animal organ development | forebrain development | negative regulation of neuron differentiation | positive regulation of G-protein coupled receptor protein signaling pathway | cytoskeleton organization | establishment of protein localization | cell-cell adhesion | adult behavior | interneuron migration from the subpallium to the cortex | regulation of glial cell differentiation | regulation of cell communication | cell adhesion mediator activity | regulation of gliogenesis | positive regulation of protein maturation | interneuron migration | glial cell development | cell development | protein localization | protein localization to juxtaparanode region of axon | anatomical structure morphogenesis | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | receptor-mediated endocytosis | regulation of G-protein coupled receptor protein signaling pathway | developmental process | organelle organization | receptor metabolic process | central nervous system development | cell-cell adhesion via plasma-membrane adhesion molecules | positive regulation of metabolic process | regulation of synaptic plasticity | regulation of cell projection organization | cellular metabolic process | regulation of astrocyte differentiation | negative regulation of cell development | chemotaxis | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | homophilic cell adhesion via plasma membrane adhesion molecules | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

integral component of membrane | synapse | neuron projection | potassium channel complex | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | main axon | protein-containing complex | cell projection | plasma membrane | voltage-gated potassium channel complex | node of Ranvier | anchored component of membrane | integral component of plasma membrane | juxtaparanode region of axon | cell periphery | axon | transmembrane transporter complex | cation channel complex | ion channel complex | cell surface | myelin sheath | membrane | intrinsic component of plasma membrane