QuickView for corticotropin receptor (gene)

Gene Symbol:

MC2R Homo sapiens

Full name:

melanocortin 2 receptor

Synonyms:

ACTHR, adrenocorticotropic hormone receptor, ACTH receptor, MC2 receptor, adrenocorticotropin receptor, corticotropin receptor, melanocortin 2 receptor (adrenocorticotropic hormone)

Genomic Location:

Chr 18: 13872043-13905535

Description:

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a v...

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MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTTGT_LEF1_Q2

Cytogenetic Map:

18p11.21

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