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Name: Cytochrome P-450 CYP2D6
Description: A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
Synonyms:
P-450 CYP2D6, Cytochrome; 2-Hydroxylase, Imipramine; P450 2D6, Cytochrome; CYP 2D6; Debrisoquine 4-Hydroxylase; Debrisoquine 4-Monooxygenase; Debrisoquine Hydroxylase; Imipramine 2-Hydroxylase; Hydroxylase, Debrisoquine; 4-Monooxygenase, Debrisoquine.
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