QuickView for cytokeratin 19 (gene)

Gene Symbol:

KRT19 Homo sapiens

Full name:

keratin 19

Synonyms:

CK19, K19, K1CS, keratin, type I cytoskeletal 19, 40-kDa keratin intermediate filament, CK-19, cytokeratin 19, keratin 19, type I, keratin, type I, 40-kd

Genomic Location:

Chr 17: 36933395-36938167

Description:

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike ...

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The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  GCANCTGNY_MYOD_Q6 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  AP1_Q4 ,  BACH1_01 ,  CAGCTG_AP4_Q5

Cytogenetic Map:

17q21.2

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