QuickView for dSirt2 (gene)
- Gene Symbol:
- Sirt2
D. melanogaster - Full name:
- CG5085 gene product from transcript CG5085-RA
- Synonyms:
- CG5085, D.mel2, DmelCG5085, Dmel_CG5085, dSIRT2
- Genomic Location:
- Chr 3R: 16154192-16155753
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Bos taurus , Gallus gallus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | nucleotide binding | coenzyme binding | hydrolase activity | protein deacetylase activity | NAD+ binding | catalytic activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | NAD-dependent protein deacetylase activity | anion binding | histone deacetylase activity | ion binding | organic cyclic compound binding | NAD-dependent histone deacetylase activity | zinc ion binding | NAD binding | transition metal ion binding | deacetylase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
cellular response to decreased oxygen levels | regulation of programmed cell death | negative regulation of cellular process | negative regulation of RNA biosynthetic process | histone modification | histone deacetylation | cellular process | chromatin organization | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | response to hypoxia | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | cellular component organization | response to stimulus | cellular response to hypoxia | response to stress | regulation of cell proliferation | negative regulation of metabolic process | protein modification process | protein deacetylase activity | macromolecule modification | histone H3 deacetylation | regulation of nucleic acid-templated transcription | response to oxygen levels | nitrogen compound metabolic process | multicellular organism development | NAD-dependent protein deacetylase activity | regulation of gene expression | histone deacetylase activity | cellular response to stress | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | protein deacetylation | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia | NAD-dependent histone deacetylase activity | regulation of cellular metabolic process | regulation of RNA metabolic process | protein metabolic process | anatomical structure development | metabolic process | regulation of DNA-templated transcription in response to stress | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of transcription from RNA polymerase II promoter in response to stress | multicellular organism aging | covalent chromatin modification | regulation of transcription, DNA-templated | determination of adult lifespan | cellular protein metabolic process | regulation of transcription from RNA polymerase II promoter in response to stress | regulation of transcription from RNA polymerase II promoter in response to hypoxia | developmental process | organelle organization | cellular protein modification process | negative regulation of transcription by RNA polymerase II | negative regulation of cell proliferation | chromosome organization | cellular metabolic process | regulation of cell death | negative regulation of cell death | aging | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
