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QuickView for dynamin-3 (gene)


Gene Symbol:
DNM3 Homo sapiens Homo sapiens
Full name:
dynamin 3
Synonyms:
Dyna III, dynamin-3, T-dynamin, dynamin family member, dynamin, testicular
Genomic Location:
Chr 1: 170077261-170648480
Description:
This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1q24.3





GO Molecular Function

type 1 metabotropic glutamate receptor binding | guanyl ribonucleotide binding | ribonucleoside binding | G-protein coupled glutamate receptor binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | type 5 metabotropic glutamate receptor binding | pyrophosphatase activity | catalytic activity | cytoskeletal protein binding | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | nitric-oxide synthase binding | G-protein coupled receptor binding | GTP binding | hydrolase activity, acting on acid anhydrides | microtubule binding | nucleoside binding | purine ribonucleotide binding | tubulin binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | glutamate receptor binding | small molecule binding

GO Biological Process

positive regulation of cellular component organization | regulation of cell morphogenesis | positive regulation of filopodium assembly | regulation of neurogenesis | regulation of cellular localization | regulation of cell development | regulation of localization | establishment of localization | negative regulation of cellular process | neurotransmitter receptor internalization | cell differentiation | negative regulation of dendrite development | nervous system development | neurogenesis | generation of neurons | membrane organization | intracellular transport | cellular process | establishment of organelle localization | regulation of dendritic spine morphogenesis | localization | negative regulation of synapse organization | synapse assembly | regulation of neuron projection development | synaptic vesicle budding | establishment of localization in cell | regulation of cell differentiation | regulation of cellular process | organelle localization | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | synaptic vesicle budding from presynaptic endocytic zone membrane | positive regulation of synaptic vesicle recycling | negative regulation of dendritic spine morphogenesis | negative regulation of neuron projection development | cellular localization | cellular component assembly | regulation of synapse structure or activity | synaptic vesicle cycle | regulation of cell projection assembly | system development | multicellular organism development | negative regulation of dendritic spine development | localization within membrane | synaptic vesicle recycling | regulation of neuron differentiation | cell projection assembly | regulation of synapse organization | positive regulation of cell projection organization | vesicle-mediated transport | synapse organization | establishment of vesicle localization | negative regulation of dendrite morphogenesis | receptor internalization | synaptic vesicle endocytosis | protein-containing complex localization | positive regulation of transport | regulation of filopodium assembly | postsynaptic neurotransmitter receptor internalization | regulation of cell morphogenesis involved in differentiation | negative regulation of cell projection organization | import into cell | anatomical structure development | regulation of dendrite morphogenesis | cell projection organization | metabolic process | endocytosis | filopodium assembly | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of neuron differentiation | vesicle organization | vesicle budding from membrane | regulation of postsynapse organization | regulation of dendrite development | regulation of dendritic spine development | synaptic vesicle localization | positive regulation of plasma membrane bounded cell projection assembly | regulation of synaptic vesicle recycling | regulation of nervous system development | regulation of developmental process | receptor-mediated endocytosis | developmental process | organelle organization | regulation of transport | receptor metabolic process | vesicle localization | regulation of cell projection organization | cellular metabolic process | synaptic vesicle transport | negative regulation of cell development | negative regulation of cell differentiation | regulation of cellular component organization | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

supramolecular fiber | synaptic cleft | dendritic spine | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | basal tubulobulbar complex | somatodendritic compartment | cytoplasmic vesicle | cell | synaptic membrane | microtubule | cytoplasm | intracellular organelle | dendritic tree | Golgi apparatus | protein-containing complex | cell projection | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | postsynaptic endocytic zone | plasma membrane | apical tubulobulbar complex | photoreceptor inner segment | dendritic spine head | vesicle | perinuclear region of cytoplasm | postsynaptic density | extracellular exosome | microtubule cytoskeleton | asymmetric synapse | tubulobulbar complex | extracellular region | postsynaptic endocytic zone membrane | membrane-bounded organelle | extracellular vesicle | organelle | postsynaptic specialization | extracellular space | cell periphery | axon | intracellular vesicle | cytoskeleton | intracellular | membrane | supramolecular complex