QuickView for eNOS (gene)
- Gene Symbol:
- Nos3
Mus musculus - Full name:
- nitric oxide synthase 3, endothelial cell
- Synonyms:
- 2310065A03Rik, Nos-3, eNOS, ecNOS, nitric oxide synthase, endothelial, EC-NOS, NOS type III, NOSIII, cNOS, constitutive NOS, endothelial NOS, endothelial nitric oxide synthase
- Genomic Location:
- Chr 5: 23870637-23890289
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
beta-catenin binding | actin binding | oxidoreductase activity, acting on NAD(P)H | NADP binding | cofactor binding | cadherin binding | cation binding | carboxylic acid binding | enzyme binding | ribonucleotide binding | FMN binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | carbohydrate derivative binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cytoskeletal protein binding | anion binding | amino acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | scaffold protein binding | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | ion binding | organic cyclic compound binding | tetrahydrobiopterin binding | cell adhesion molecule binding | tetrapyrrole binding | protein binding | arginine binding | nitric-oxide synthase activity | nitric-oxide synthase binding | NADPH-hemoprotein reductase activity | Hsp90 protein binding | heme binding | actin monomer binding | drug binding | calmodulin binding | heat shock protein binding | organic acid binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
positive regulation of cyclase activity | smooth muscle hyperplasia | regulation of muscle system process | oxidoreductase activity, acting on NAD(P)H | positive regulation of locomotion | regulation of systemic arterial blood pressure by hormone | cell motility | response to lipopolysaccharide | developmental process involved in reproduction | positive regulation of lyase activity | intracellular signal transduction | positive regulation of apoptotic process | homeostasis of number of cells within a tissue | regulation of localization | regulation of the force of heart contraction by chemical signal | gonad development | regulation of programmed cell death | regulation of sodium ion transport | female gonad development | superoxide metabolic process | nitric oxide biosynthetic process | response to hormone | negative regulation of potassium ion transport | negative regulation of cellular process | positive regulation of developmental process | respiratory tube development | reactive oxygen species metabolic process | epithelial cell migration | pulmonary valve development | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | mesenchyme development | tissue homeostasis | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular amino acid catabolic process | cellular process | organic substance catabolic process | regulation of cell motility | localization | cellular detoxification | tissue remodeling | heart morphogenesis | reproductive system development | response to estradiol | epithelium migration | multicellular organismal reproductive process | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | tissue development | gamete generation | anatomical structure homeostasis | ventricular septum morphogenesis | cellular amino acid metabolic process | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | catabolic process | cellular response to molecule of bacterial origin | regulation of systemic arterial blood pressure mediated by a chemical signal | response to transforming growth factor beta | positive regulation of epithelial cell migration | negative regulation of biomineral tissue development | development of primary sexual characteristics | regulation of vasculature development | response to stimulus | ovulation | vasculature development | female gamete generation | cellular response to mechanical stimulus | respiratory system development | blood vessel remodeling | regulation of blood vessel size | carboxylic acid catabolic process | response to stress | endothelial cell migration | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | ovulation cycle | multicellular organismal homeostasis | tube morphogenesis | regulation of blood circulation | development of primary female sexual characteristics | reproduction | cardiovascular system development | rhythmic process | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to toxic substance | regulation of guanylate cyclase activity | negative regulation of transport | positive regulation of blood vessel endothelial cell migration | blood circulation | reactive oxygen species biosynthetic process | cellular biosynthetic process | embryo development | ovulation from ovarian follicle | negative regulation of blood pressure | blood vessel development | pulmonary valve morphogenesis | regulation of neurotransmitter levels | locomotion | endocardial cushion development | positive regulation of guanylate cyclase activity | response to external biotic stimulus | system development | removal of superoxide radicals | nitrogen compound metabolic process | reproductive process | multicellular organism development | negative regulation of catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | cell migration | monooxygenase activity | regulation of catalytic activity | cellular response to oxidative stress | nitric oxide mediated signal transduction | regulation of gene expression | cellular response to stress | response to lipid | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | regulation of blood pressure | endocardial cushion morphogenesis | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | animal organ morphogenesis | negative regulation of smooth muscle cell proliferation | response to superoxide | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | negative regulation of muscle hyperplasia | regulation of cellular component movement | response to oxidative stress | response to oxygen radical | regulation of the force of heart contraction | regulation of endothelial cell migration | second-messenger-mediated signaling | homeostasis of number of cells | neurotransmitter metabolic process | positive regulation of cell migration | biosynthetic process | aortic valve morphogenesis | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | angiogenesis | mesenchyme morphogenesis | negative regulation of ion transport | cardiac septum morphogenesis | response to toxic substance | regulation of systemic arterial blood pressure by endothelin | regulation of cyclase activity | regulation of heart contraction | ovulation cycle process | response to bacterium | chordate embryonic development | endocrine process | cell communication | regulation of cellular metabolic process | semi-lunar valve development | negative regulation of calcium ion transport | heart development | homeostatic process | arginine catabolic process | regulation of locomotion | embryo development ending in birth or egg hatching | lipopolysaccharide-mediated signaling pathway | regulation of tube size | drug metabolic process | carboxylic acid metabolic process | regulation of potassium ion transport | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | multicellular organism reproduction | reactive nitrogen species metabolic process | heart valve development | ventricular septum development | cardiac ventricle development | response to organic substance | tissue morphogenesis | nitric-oxide synthase activity | response to mechanical stimulus | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cellular oxidant detoxification | oxidation-reduction process | positive regulation of cell death | cellular response to reactive oxygen species | heart valve morphogenesis | organic substance metabolic process | animal organ development | response to reactive oxygen species | positive regulation of programmed cell death | regulation of phosphate metabolic process | positive regulation of endothelial cell migration | lung development | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | organonitrogen compound catabolic process | neurotransmitter biosynthetic process | arginine metabolic process | regulation of blood vessel endothelial cell migration | negative regulation of molecular function | NADPH-hemoprotein reductase activity | signaling | response to organic cyclic compound | organic acid metabolic process | anatomical structure morphogenesis | response to biotic stimulus | reproductive structure development | regulation of developmental process | regulation of ion transport | developmental process | nitric oxide metabolic process | regulation of calcium ion transport | cardiac septum development | tube development | regulation of transport | aortic valve development | negative regulation of cell proliferation | detoxification | smooth muscle adaptation | cardiac chamber development | negative regulation of hydrolase activity | cellular response to superoxide | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | sex differentiation | regulation of smooth muscle cell proliferation | positive regulation of cell motility | oxidoreductase activity | circulatory system development | sexual reproduction | positive regulation of angiogenesis | muscle system process | response to other organism | signal transduction | positive regulation of gene expression | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | sarcolemma | organelle membrane | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | membrane microdomain | apical part of cell | Golgi apparatus | endomembrane system | plasma membrane | membrane raft | vesicle | mitochondrion | membrane-bounded organelle | nucleus | organelle | vesicle membrane | cell periphery | membrane-enclosed lumen | plasma membrane raft | cytosol | cytoskeleton | intracellular | caveola | membrane
