Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for eif 2 kinase (compound)


Name: eIF-2 Kinase
Description: A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.
Synonyms:
Heme-Regulated eIF-2alpha Kinase; Kinase, eIF-2alpha; RNA Dependent Protein Kinase; Kinase, TIK; Kinase, Heme-Regulated eIF-2alpha; Double Stranded RNA-Dependent Kinase (dsl); Heme Controlled Translational Repressor; Protein Kinase, RNA Activated; DSRNA Dep Protein Kinase; DAI Protein Kinase.
show more »