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QuickView for endothelin a receptor (gene)


Gene Symbol:
Ednra Mus musculus Mus musculus
Full name:
endothelin receptor type A
Synonyms:
AEA001, ET-AR, ETa, Gpcr10, Mhdaaea1, endothelin-1 receptor, ET-A, G-protein coupled receptor 10, endothelin A receptor
Genomic Location:
Chr 8: 80186928-80248351
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_010332
Protein Names
Q61614
O54993
Q91VV2



GO Molecular Function

transmembrane signaling receptor activity | G-protein coupled receptor activity | catalytic activity | signaling receptor activity | endothelin receptor activity | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | peptide receptor activity | G-protein coupled peptide receptor activity | kinase activity

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | regulation of leukocyte chemotaxis | regulation of ERK1 and ERK2 cascade | respiratory gaseous exchange | regulation of blood vessel diameter | positive regulation of locomotion | renal filtration | response to lipopolysaccharide | regulation of cellular localization | intracellular signal transduction | regulation of localization | morphogenesis of an epithelium | response to isoquinoline alkaloid | regulation of programmed cell death | vascular smooth muscle contraction | peptidyl-amino acid modification | establishment of localization | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | response to drug | cellular chemical homeostasis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | tonic smooth muscle contraction | mesenchyme development | blood vessel morphogenesis | fibroblast proliferation | histamine secretion | artery smooth muscle contraction | cellular process | secretion | response to morphine | regulation of cell motility | localization | cellular homeostasis | epithelial tube morphogenesis | glomerular filtration | azole transport | multicellular organismal reproductive process | regulation of chemotaxis | negative regulation of apoptotic process | response to hypoxia | positive regulation of nitrogen compound metabolic process | tissue development | histamine transport | autonomic nervous system development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of neutrophil migration | regulation of cytosolic calcium ion concentration | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | smooth muscle contraction | calcium ion homeostasis | regulation of neutrophil chemotaxis | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | head development | G-protein coupled receptor activity | muscle contraction | branching involved in blood vessel morphogenesis | response to stimulus | vasculature development | cellular response to mechanical stimulus | mesenchymal cell development | positive regulation of immune system process | positive regulation of protein metabolic process | regulation of blood vessel size | response to stress | positive regulation of cation transmembrane transport | regulation of cell proliferation | tube morphogenesis | reproduction | cardiovascular system development | response to molecule of bacterial origin | blood circulation | G-protein coupled receptor signaling pathway | protein modification process | regulation of odontogenesis | embryo development | macromolecule modification | metal ion homeostasis | blood vessel development | negative regulation of blood vessel diameter | response to nitrogen compound | regulation of calcium ion transport into cytosol | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of inflammatory response | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of granulocyte chemotaxis | regulation of phosphorylation | positive regulation of chemotaxis | organic substance transport | response to lipid | nervous system process | copulation | regulation of blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to ammonium ion | positive regulation of ion transmembrane transport | enteric nervous system development | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | endothelin receptor activity | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of release of sequestered calcium ion into cytosol | stem cell differentiation | positive regulation of cell migration | cell proliferation | sensory perception of pain | endothelin receptor signaling pathway | regulation of cellular protein metabolic process | vasoconstriction | angiogenesis | phosphorylation | regulation of calcium ion transmembrane transport | positive regulation of odontogenesis | response to xenobiotic stimulus | protein phosphorylation | cation homeostasis | regulation of leukocyte migration | phosphate-containing compound metabolic process | response to bacterium | chordate embryonic development | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of tube size | positive regulation of transport | protein tyrosine kinase activity | multicellular organism reproduction | protein metabolic process | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | Rho protein signal transduction | branching morphogenesis of an epithelial tube | response to mechanical stimulus | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | metabolic process | mesenchymal cell differentiation | regulation of neutrophil migration | negative regulation of programmed cell death | smooth muscle cell proliferation | positive regulation of neutrophil chemotaxis | regulation of tube diameter | chemical homeostasis | protein kinase activity | organic substance metabolic process | regulation of sequestering of calcium ion | mating | regulation of glucose transmembrane transport | animal organ development | positive regulation of ion transport | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | regulation of ion transmembrane transport | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | positive regulation of MAPK cascade | stem cell development | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | sensory perception | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | muscle cell proliferation | signaling | G-protein coupled peptide receptor activity | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | cation transport | positive regulation of calcium ion transport into cytosol | response to biotic stimulus | ammonium transport | regulation of developmental process | regulation of ion transport | kinase activity | developmental process | regulation of calcium ion transport | cellular protein modification process | tube development | regulation of transport | Ras protein signal transduction | neurotransmitter transport | positive regulation of kidney development | response to organonitrogen compound | neural crest cell differentiation | positive regulation of granulocyte chemotaxis | cellular metal ion homeostasis | response to anesthetic | in utero embryonic development | positive regulation of metabolic process | ion transport | cellular metabolic process | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | circulatory system development | regulation of inflammatory response | divalent inorganic cation homeostasis | penile erection | neural crest cell development | sexual reproduction | positive regulation of calcium ion transport | muscle system process | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | organelle membrane | nuclear membrane | cell | intrinsic component of membrane | intracellular organelle | membrane microdomain | endomembrane system | plasma membrane | nuclear envelope | membrane raft | T-tubule | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane