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QuickView for erythromycin N-demethylase (compound)


Name: Cytochrome P-450 CYP3A
Description: A cytochrome P-450 monooxygenase that is involved in an NADPH-dependent electron transport pathway by oxidizing a variety of structurally unrelated compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN.
Synonyms:
CYP3A; N-Demethylase, Erythromycin; Cytochrome P-450IIIA; Cytochrome P 450IIIA; P-450 CYP3A, Cytochrome; Cytochrome P 450 CYP3A; Erythromycin N Demethylase; Cytochrome P450 3A; P-450IIIA, Cytochrome; P450 3A, Cytochrome.
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