Name: | Fibrinogen |
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Description: | Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. |
Synonyms: |
Factor I, Coagulation; Coagulation Factor I; Fibrinogens; Blood Coagulation Factor I; Factor I; I, Coagulation Factor
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