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QuickView for factor xa (gene)


Gene Symbol:
F10 Homo sapiens Homo sapiens
Full name:
coagulation factor X
Synonyms:
FX, FXA, coagulation factor X, Stuart-Prower factor, factor Xa, prothrombinase
Genomic Location:
Chr 13: 112825114-112851844
Description:
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 E...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 13
13q34


Transcripts Names
NM_000504
NM_001312675
NM_001312674
Protein Names
Q5JVE7
Q5JVE8
Q14340
P00742



GO Molecular Function

cation binding | lipid binding | hydrolase activity | phospholipid binding | catalytic activity | serine hydrolase activity | anion binding | ion binding | protein binding | serine-type endopeptidase activity | serine-type peptidase activity | calcium ion binding | endopeptidase activity | metal ion binding | peptidase activity

GO Biological Process

positive regulation of locomotion | proteolysis | regulation of localization | blood coagulation, extrinsic pathway | establishment of localization | positive regulation of cellular component movement | intracellular transport | regulation of cell motility | localization | hemostasis | establishment of localization in cell | regulation of protein kinase B signaling | regulation of cellular process | response to stimulus | response to stress | cellular localization | blood coagulation | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of protein kinase B signaling | wound healing | blood coagulation, fibrin clot formation | regulation of cell migration | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of cellular component movement | positive regulation of cell migration | protein activation cascade | positive regulation of signal transduction | regulation of locomotion | Golgi vesicle transport | coagulation | protein metabolic process | response to wounding | regulation of intracellular signal transduction | metabolic process | regulation of body fluid levels | organic substance metabolic process | serine-type endopeptidase activity | serine-type peptidase activity | regulation of cell communication | ER to Golgi vesicle-mediated transport | endopeptidase activity | peptidase activity | positive regulation of cell motility | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | intrinsic component of external side of plasma membrane | cell | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | endomembrane system | plasma membrane | endoplasmic reticulum lumen | extracellular region | membrane-bounded organelle | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cell surface | intracellular | membrane | intrinsic component of plasma membrane | Golgi lumen