QuickView for ficolin-1 (gene)

Gene Symbol:

FCN1 Homo sapiens

Full name:

ficolin 1

Synonyms:

FCNM, ficolin-1, M-ficolin, ficolin (collagen/fibrinogen domain-containing) 1, ficolin-A, ficolin-alpha

Genomic Location:

Chr 9: 136941253-136949630

Description:

The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collecti...

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The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

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Orthologs:

Mus musculus ,  Rattus norvegicus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MGGAAGTG_GABP_B

Cytogenetic Map:

9q34.3

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