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QuickView for ficolin-2 (gene)


Gene Symbol:
FCN2 Homo sapiens Homo sapiens
Full name:
ficolin 2
Synonyms:
EBP-37, FCNL, P35, ficolin-2, ficolin-2, 37 kDa elastin-binding protein, L-ficolin, collagen/fibrinogen domain-containing protein 2, ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin), ficolin B, ficolin-beta, serum lectin p35
Genomic Location:
Chr 9: 136912479-136919187
Description:
The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic ...
Orthologs:
Macaca mulatta Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 9
9q34.3





GO Molecular Function

proteoglycan binding | cation binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | serine hydrolase activity | calcium-dependent protein binding | antigen binding | ion binding | carbohydrate binding | protein binding | mannan binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | metal ion binding | peptidase activity | polysaccharide binding

GO Biological Process

positive regulation of immune response | proteolysis | complement activation | defense response to other organism | establishment of localization | regulation of immune system process | opsonization | defense response | defense response to Gram-negative bacterium | cellular process | localization | cell recognition | regulation of immune response | response to stimulus | positive regulation of immune system process | response to stress | apoptotic cell clearance | response to external biotic stimulus | nitrogen compound metabolic process | recognition of apoptotic cell | vesicle-mediated transport | protein activation cascade | response to bacterium | humoral immune response | defense response to bacterium | activation of immune response | protein metabolic process | import into cell | phagocytosis, recognition | metabolic process | endocytosis | immune response | organic substance metabolic process | serine-type endopeptidase activity | serine-type peptidase activity | defense response to Gram-positive bacterium | complement activation, lectin pathway | endopeptidase activity | response to biotic stimulus | innate immune response | immune system process | peptidase activity | phagocytosis | response to other organism | macromolecule metabolic process

GO Cellular Component

protein-containing complex | vesicle | collagen trimer | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | blood microparticle