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QuickView for filgrastim (gene)


Gene Symbol:
CSF3 Homo sapiens Homo sapiens
Full name:
colony stimulating factor 3
Synonyms:
C17orf33, CSF3OS, GCSF, granulocyte colony-stimulating factor, colony stimulating factor 3 (granulocyte), filgrastim, granulocyte-colony stimulating factor, lenograstim, pluripoietin
Genomic Location:
Chr 17: 35425214-35427592
Description:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17q21.1





GO Molecular Function

enzyme binding | signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity | granulocyte colony-stimulating factor receptor binding | growth factor receptor binding

GO Biological Process

regulation of supramolecular fiber organization | positive regulation of macromolecule biosynthetic process | response to cytokine | positive regulation of cellular component organization | response to lipopolysaccharide | positive regulation of DNA-binding transcription factor activity | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | myeloid cell differentiation | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | response to drug | positive regulation of phosphate metabolic process | regulation of organelle organization | regulation of actin polymerization or depolymerization | response to antibiotic | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | positive regulation of actin filament polymerization | positive regulation of peptidyl-serine phosphorylation | immune system development | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of binding | regulation of cell differentiation | regulation of protein kinase B signaling | regulation of cellular process | cellular response to lipid | regulation of metabolic process | regulation of protein complex assembly | cellular response to molecule of bacterial origin | positive regulation of cellular protein metabolic process | cellular component organization | positive regulation of protein binding | regulation of actin filament length | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of phosphatidylinositol 3-kinase signaling | regulation of cell proliferation | response to alcohol | response to molecule of bacterial origin | regulation of cellular component size | positive regulation of RNA biosynthetic process | hemopoiesis | regulation of actin cytoskeleton reorganization | molecular function regulator | response to ethanol | regulation of nucleic acid-templated transcription | leukocyte differentiation | response to external biotic stimulus | system development | regulation of signal transduction | positive regulation of organelle organization | regulation of actin cytoskeleton organization | multicellular organism development | regulation of actin filament organization | positive regulation of protein kinase B signaling | regulation of phosphorylation | regulation of gene expression | response to lipid | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | positive regulation of actin cytoskeleton reorganization | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | granulocyte differentiation | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | response to toxic substance | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of actin filament polymerization | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of molecular function | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | receptor ligand activity | immune response | positive regulation of cellular component biogenesis | cytokine activity | animal organ development | regulation of phosphate metabolic process | positive regulation of binding | regulation of peptidyl-serine phosphorylation | regulation of cell communication | signaling | regulation of transcription, DNA-templated | regulation of protein binding | positive regulation of phosphorylation | response to biotic stimulus | regulation of developmental process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of protein polymerization | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | regulation of actin filament-based process | immune system process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | negative regulation of cell death | regulation of cellular component organization | regulation of cytoskeleton organization | response to other organism | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | cellular response to lipopolysaccharide | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

extracellular region | extracellular space