QuickView for gaba modulators (compound)

Name:	GABA Modulators
Description:	Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
Synonyms:	Modulators, GABA; Modulators, GABAergic; gamma-Aminobutyric Acid Modulators; Modulators, gamma-Aminobutyric Acid; GABAergic Modulators; Acid Modulators, gamma-Aminobutyric; gamma Aminobutyric Acid Modulators