Correlation Engine 2.0
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QuickView for glucosylceramide synthase (gene)


Gene Symbol:
UGCG Homo sapiens Homo sapiens
Full name:
UDP-glucose ceramide glucosyltransferase
Synonyms:
GCS, GLCT1, ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, glucosylceramide synthase
Genomic Location:
Chr 9: 113699027-113735260
Description:
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 9
9q31.3


Transcripts Names
NM_003358
XM_005252186
XM_017015107
Protein Names
Q16739
A0A024R157
Q5T258



GO Molecular Function

UDP-glucosyltransferase activity | UDP-glycosyltransferase activity | catalytic activity | glucosyltransferase activity | transferase activity, transferring glycosyl groups | transferase activity, transferring hexosyl groups | transferase activity | ceramide glucosyltransferase activity | dihydroceramide glucosyltransferase activity

GO Biological Process

glycosphingolipid metabolic process | glycolipid biosynthetic process | cellular process | sphingolipid metabolic process | tissue development | glucosylceramide biosynthetic process | cellular lipid metabolic process | glycosphingolipid biosynthetic process | cellular nitrogen compound biosynthetic process | ceramide metabolic process | glucosylceramide metabolic process | sphingolipid biosynthetic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cellular biosynthetic process | nitrogen compound metabolic process | lipid metabolic process | cellular amide metabolic process | glycolipid metabolic process | biosynthetic process | lipid biosynthetic process | glycosylceramide metabolic process | epidermis development | anatomical structure development | metabolic process | membrane lipid metabolic process | organic substance metabolic process | amide biosynthetic process | developmental process | carbohydrate derivative metabolic process | cellular metabolic process | ceramide biosynthetic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | Golgi membrane | membrane-bounded organelle | organelle | intracellular | membrane