QuickView for hCAR (gene)
- Gene Symbol:
- CXADR
Homo sapiens - Full name:
- CXADR, Ig-like cell adhesion molecule
- Synonyms:
- CAR, CAR4/6, HCAR, coxsackievirus and adenovirus receptor, 46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3-binding protein, HCVADR, coxsackie virus and adenovirus receptor, coxsackievirus B-adenovirus receptor
- Genomic Location:
- Chr 21: 17807201-17861147
- Description:
-
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
OCT1_07 , TTANTCA_UNKNOWN , RYTTCCTG_ETS2_B , FOXD3_01 , STAT6_01 , WHN_B , GTGACGY_E4F1_Q6 , CAGGTG_E12_Q6 , YY1_01 , TST1_01
- Cytogenetic Map:
-
21q21.1
GO Molecular Function
beta-catenin binding | cell adhesive protein binding involved in AV node cell-bundle of His cell communication | protein binding involved in heterotypic cell-cell adhesion | protein-containing complex binding | cell-cell adhesion mediator activity | signaling receptor binding | protein domain specific binding | integrin binding | cell adhesion molecule binding | protein binding | virus receptor activity | connexin binding | cell adhesion mediator activity | PDZ domain binding
GO Biological Process
actin filament-based process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | cell motility | muscle tissue development | heterotypic cell-cell adhesion | actin cytoskeleton organization | establishment of localization | regulation of immune system process | epithelial structure maintenance | cell differentiation | striated muscle cell development | cardiac cell development | tissue homeostasis | cellular process | localization | cell adhesive protein binding involved in AV node cell-bundle of His cell communication | protein binding involved in heterotypic cell-cell adhesion | multicellular organismal reproductive process | granulocyte chemotaxis | transepithelial transport | tissue development | gamete generation | interspecies interaction between organisms | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | regulation of immune response | regulation of cellular process | leukocyte activation | cell-cell adhesion mediator activity | cellular component organization | entry into host cell | viral life cycle | T cell activation | response to stimulus | muscle cell development | neutrophil chemotaxis | multicellular organismal homeostasis | regulation of blood circulation | cardiac muscle tissue development | reproduction | mitochondrion organization | cell chemotaxis | muscle fiber development | leukocyte migration | regulation of membrane potential | locomotion | system development | reproductive process | AV node cell-bundle of His cell adhesion involved in cell communication | multicellular organism development | cell migration | cardiac muscle cell-cardiac muscle cell adhesion | viral entry into host cell | cardiocyte differentiation | cardiac muscle cell development | cardiac muscle fiber development | regulation of heart contraction | striated muscle tissue development | cell communication | regulation of cardiac muscle cell action potential | regulation of AV node cell action potential | leukocyte chemotaxis | heart development | homeostatic process | viral process | striated muscle cell differentiation | lymphocyte activation | multicellular organism reproduction | anatomical structure development | AV node cell to bundle of His cell communication | cell communication involved in cardiac conduction | actin cytoskeleton reorganization | cell adhesion | virus receptor activity | animal organ development | cytoskeleton organization | cell-cell adhesion | cell activation | regulation of action potential | cardiac muscle cell differentiation | regulation of cell communication | cell adhesion mediator activity | signaling | cell development | germ cell migration | developmental process | organelle organization | regulation of cardiac conduction | gamma-delta T cell activation | cell-cell adhesion via plasma-membrane adhesion molecules | immune system process | neutrophil migration | circulatory system development | chemotaxis | sexual reproduction | homotypic cell-cell adhesion | regulation of signaling | cardiac conduction | multicellular organismal process | cell-cell junction organization
GO Cellular Component
secretory granule | occluding junction | integral component of membrane | intracellular membrane-bounded organelle | neuron projection | adherens junction | cytoplasmic vesicle | cell body | actin-based cell projection | cell | nuclear lumen | distal axon | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | membrane microdomain | cell-cell adherens junction | cell-cell junction | protein-containing complex | cell projection | secretory vesicle | endomembrane system | nucleoplasm | plasma membrane | membrane raft | vesicle | site of polarized growth | integral component of plasma membrane | extracellular region | membrane-bounded organelle | apicolateral plasma membrane | filopodium | apical junction complex | nucleus | organelle | cell periphery | bicellular tight junction | axon | membrane-enclosed lumen | basolateral plasma membrane | growth cone | intracellular vesicle | intracellular | cell junction | membrane | intrinsic component of plasma membrane
