Name: | Hirudins |
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PubChem Substance ID: | 167195 |
Description: | Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN. |
Synonyms: |
Exhirud; 8001-27-2; Irudil; HIRUDIN; EINECS 232-279-1; Hirudex; Hirucreme; Recombinant hirudin
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