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QuickView for iceberg (gene)


Gene Symbol:
CARD18 Homo sapiens Homo sapiens
Full name:
caspase recruitment domain family member 18
Synonyms:
ICEBERG, UNQ5804, pseudo-ICE, caspase recruitment domain-containing protein 18, ICEBERG caspase-1 inhibitor, caspase-1 inhibitor Iceberg
Genomic Location:
Chr 11: 104513879-104515663
Orthologs:
Macaca mulatta
External Links:
Entrez Gene
Cytogenetic Map:
chr 11
11q22.3


Transcripts Names
NM_021571
Protein Names
A2RRF8
P57730



GO Molecular Function

endopeptidase inhibitor activity | enzyme binding | caspase binding | enzyme inhibitor activity | CARD domain binding | molecular function regulator | protein domain specific binding | protein binding | peptidase inhibitor activity | enzyme regulator activity | protease binding | cysteine-type endopeptidase inhibitor activity

GO Biological Process

regulation of interleukin-1 beta production | regulation of cysteine-type endopeptidase activity | endopeptidase inhibitor activity | negative regulation of peptide secretion | regulation of localization | regulation of programmed cell death | negative regulation of cysteine-type endopeptidase activity | negative regulation of cellular process | defense response | negative regulation of protein secretion | negative regulation of proteolysis | negative regulation of secretion | regulation of proteolysis | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | negative regulation of interleukin-1 production | regulation of apoptotic process | regulation of metabolic process | negative regulation of cytokine secretion | regulation of peptide secretion | response to stimulus | enzyme inhibitor activity | negative regulation of protein transport | response to stress | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of protein processing | regulation of peptide transport | molecular function regulator | negative regulation of secretion by cell | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | regulation of gene expression | negative regulation of cytokine production | inhibition of cysteine-type endopeptidase activity | regulation of nitrogen compound metabolic process | negative regulation of binding | regulation of cellular protein metabolic process | negative regulation of interleukin-1 secretion | regulation of interleukin-1 production | negative regulation of protein binding | regulation of cellular metabolic process | inflammatory response | negative regulation of protein processing | regulation of protein metabolic process | regulation of cytokine secretion | regulation of establishment of protein localization | regulation of interleukin-1 beta secretion | regulation of secretion | negative regulation of gene expression | negative regulation of cellular protein metabolic process | regulation of protein secretion | negative regulation of protein metabolic process | negative regulation of molecular function | regulation of protein binding | peptidase inhibitor activity | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | negative regulation of interleukin-1 beta secretion | negative regulation of interleukin-1 beta production | regulation of transport | negative regulation of hydrolase activity | regulation of protein localization | regulation of cell death | cysteine-type endopeptidase inhibitor activity | negative regulation of endopeptidase activity

GO Cellular Component

protein-containing complex