QuickView for inhA (gene)

Gene Symbol:

INHA Homo sapiens

Full name:

inhibin alpha subunit

Synonyms:

inhibin alpha chain, A-inhibin subunit

Genomic Location:

Chr 2: 220145198-220148671

Description:

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the ...

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This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  GATA1_01 ,  RYTTCCTG_ETS2_B ,  VDR_Q3 ,  GATA3_01 ,  GATA_Q6 ,  GATA_C ,  GCANCTGNY_MYOD_Q6 ,  GATAAGR_GATA_C ,  CTTTGA_LEF1_Q2 ,  GATA1_04 ,  COMP1_01 ,  GGGAGGRR_MAZ_Q6 ,  TFIII_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  AP4_Q6 ,  MYOD_Q6 ,  GGGCGGR_SP1_Q6 ,  LMO2COM_02 ,  E47_01 ,  GATA1_02 ,  NRF2_Q4 ,  MYOGENIN_Q6 ,  CTGCAGY_UNKNOWN ,  PAX3_B ,  CAGCTG_AP4_Q5 ,  P300_01 ,  LMO2COM_01

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Cytogenetic Map:

2q35

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