QuickView for inr (gene)
- Gene Symbol:
- InR
D. melanogaster - Full name:
- Insulin-like receptor
- Synonyms:
- CG18402, DIHR, DILR, DInR, dInsR, DIR, Dir-a, Dir-b, DIRbeta, DIRH, DmelCG18402, Dmel_CG18402, er10, InR, INR, Inr-alpha, Inr-beta, InsR, insulin/insulin-like growth factor receptor, IR, l(3)05545, l(3)93Dj, l(3)er10
- Genomic Location:
- Chr 3R: 17398221-17445043
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
phosphatidylinositol 3-kinase binding | transmembrane receptor protein tyrosine kinase activity | peptide binding | peptide hormone binding | transmembrane signaling receptor activity | ribonucleotide binding | insulin binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | amide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | hormone binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | insulin-activated receptor activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | insulin receptor substrate binding | heterocyclic compound binding | small molecule binding | protein-hormone receptor activity
GO Biological Process
response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | cell morphogenesis | myoblast fusion | embryonic development via the syncytial blastoderm | response to nutrient levels | protein heterotetramerization | regulation of neurogenesis | neuron projection morphogenesis | developmental process involved in reproduction | positive regulation of neuron remodeling | negative regulation of peptide secretion | regulation of cell development | regulation of localization | entry into diapause | syncytium formation by plasma membrane fusion | gonad development | regulation of programmed cell death | female gonad development | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | regulation of autophagy | response to hormone | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | male gamete generation | nervous system development | cellular response to extracellular stimulus | response to drug | multicellular organism growth | organ growth | cell part morphogenesis | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | intestinal stem cell homeostasis | peptidyl-tyrosine phosphorylation | regulation of peptide hormone secretion | generation of neurons | regulation of circadian sleep/wake cycle | cellular process | cell projection morphogenesis | positive regulation of neuron maturation | negative regulation of signaling | developmental growth | neuron development | reproductive system development | multicellular organismal reproductive process | negative regulation of apoptotic process | negative regulation of secretion | axon guidance | cellular response to starvation | regulation of multicellular organism growth | positive regulation of nitrogen compound metabolic process | negative regulation of hormone secretion | negative regulation of cellular metabolic process | response to peptide hormone | regulation of behavior | tissue development | regulation of cell differentiation | gamete generation | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | regulation of cell maturation | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | cellular component organization | development of primary sexual characteristics | regulation of peptide secretion | response to stimulus | female gamete generation | cell morphogenesis involved in neuron differentiation | regulation of feeding behavior | respiratory system development | positive regulation of protein metabolic process | female mating behavior | response to cocaine | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | neuron projection guidance | negative regulation of circadian rhythm | germ cell development | regulation of cell proliferation | sterol homeostasis | response to peptide | epithelial cell development | cholesterol homeostasis | circadian rhythm | response to starvation | development of primary female sexual characteristics | male germ-line stem cell asymmetric division | germ-line stem-cell niche homeostasis | reproduction | rhythmic process | negative regulation of transport | germ-line stem cell division | negative regulation of metabolic process | regulation of cellular component size | cellular component assembly | protein modification process | regulation of peptide transport | positive regulation of multicellular organism growth | embryo development | macromolecule modification | regulation of lipid storage | regulation of TOR signaling | locomotion | response to nitrogen compound | cellular response to hormone stimulus | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | syncytium formation | cellular response to peptide hormone stimulus | germ-band shortening | regulation of MAPK cascade | primary spermatocyte growth | phosphorus metabolic process | regulation of neuron maturation | protein complex oligomerization | cellular response to insulin stimulus | lipid metabolic process | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | regulation of neuron differentiation | regulation of TORC1 signaling | axon development | cellular response to stress | cellular response to peptide | stem cell division | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | positive regulation of lipid storage | oogenesis | response to oxidative stress | axonogenesis | open tracheal system development | positive regulation of cell differentiation | homeostasis of number of cells | locomotory behavior | cell division | regulation of cellular protein metabolic process | positive regulation of cell maturation | negative regulation of peptide hormone secretion | phosphorylation | triglyceride homeostasis | carbohydrate metabolic process | protein tetramerization | positive regulation of lipid localization | response to xenobiotic stimulus | regulation of circadian sleep/wake cycle, sleep | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | negative regulation of autophagy | female germ-line stem cell asymmetric division | cell communication | regulation of cellular metabolic process | asymmetric cell division | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of TOR signaling | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | striated muscle cell differentiation | embryonic morphogenesis | positive regulation of TORC1 signaling | dormancy process | protein tyrosine kinase activity | neuron differentiation | multicellular organism reproduction | protein-containing complex assembly | positive regulation of organ growth | protein metabolic process | positive regulation of protein modification process | regulation of growth | response to organic substance | negative regulation of behavior | ovarian follicle cell development | regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | reproductive behavior | cell projection organization | metabolic process | positive regulation of cell development | insulin-activated receptor activity | somatic muscle development | negative regulation of feeding behavior | negative regulation of programmed cell death | mating behavior | imaginal disc development | chemical homeostasis | regulation of secretion | behavior | protein kinase activity | neuron projection development | organic substance metabolic process | mating | animal organ development | entry into reproductive diapause | positive regulation of ERK1 and ERK2 cascade | negative regulation of circadian sleep/wake cycle, sleep | regulation of phosphate metabolic process | response to alkaloid | imaginal disc growth | positive regulation of MAPK cascade | anatomical structure formation involved in morphogenesis | regulation of neuron remodeling | multicellular organism aging | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | myotube differentiation | response to organic cyclic compound | cell development | regulation of developmental growth | determination of adult lifespan | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cell size | protein heterooligomerization | anatomical structure morphogenesis | regulation of organ growth | regulation of circadian rhythm | reproductive structure development | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | regulation of cell growth | spermatogenesis | positive regulation of cell size | cellular protein modification process | acylglycerol homeostasis | columnar/cuboidal epithelial cell development | tube development | regulation of transport | regulation of reactive oxygen species metabolic process | developmental cell growth | response to organonitrogen compound | asymmetric stem cell division | epithelial cell differentiation | response to anesthetic | transmembrane receptor protein tyrosine kinase signaling pathway | response to anoxia | positive regulation of metabolic process | positive regulation of neuron differentiation | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | negative regulation of cell death | aging | carbohydrate homeostasis | chemotaxis | sexual reproduction | lipid homeostasis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of fat cell proliferation | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | catalytic complex | neuron projection | protein kinase complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | cell projection | plasma membrane | transferase complex | integral component of plasma membrane | insulin receptor complex | cell periphery | axon | intracellular | membrane | intrinsic component of plasma membrane
