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QuickView for interleukin 7 (gene)


Gene Symbol:
IL7 Homo sapiens Homo sapiens
Full name:
interleukin 7
Synonyms:
IL-7, interleukin-7
Genomic Location:
Chr 8: 79807560-79880313
Description:
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell developmen...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8q21.13





GO Molecular Function

interleukin-7 receptor binding | signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity | growth factor receptor binding

GO Biological Process

regulation of extrinsic apoptotic signaling pathway in absence of ligand | response to cytokine | regulation of B cell activation | homeostasis of number of cells within a tissue | regulation of programmed cell death | T cell lineage commitment | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | regulation of T cell differentiation | bone remodeling | positive regulation of cell adhesion | interleukin-7-mediated signaling pathway | tissue homeostasis | positive regulation of T cell differentiation | cellular process | lymphocyte differentiation | tissue remodeling | negative regulation of signaling | immune system development | regulation of response to cytokine stimulus | negative regulation of apoptotic process | regulation of cell differentiation | anatomical structure homeostasis | negative regulation of apoptotic signaling pathway | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | bone resorption | T cell activation | response to stimulus | positive regulation of immune system process | positive regulation of lymphocyte proliferation | regulation of cell proliferation | multicellular organismal homeostasis | positive regulation of cell-cell adhesion | positive regulation of B cell proliferation | positive regulation of cell activation | positive regulation of T cell activation | hemopoiesis | regulation of cell adhesion | cell-cell signaling | molecular function regulator | regulation of lymphocyte differentiation | leukocyte differentiation | positive regulation of response to cytokine stimulus | positive regulation of mononuclear cell proliferation | system development | regulation of signal transduction | multicellular organism development | negative regulation of catalytic activity | positive regulation of lymphocyte differentiation | regulation of catalytic activity | regulation of T cell activation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | regulation of lymphocyte activation | animal organ morphogenesis | cytokine-mediated signaling pathway | positive regulation of cell differentiation | cellular response to interleukin-7 | negative regulation of extrinsic apoptotic signaling pathway | homeostasis of number of cells | cellular response to cytokine stimulus | positive regulation of chemokine production | regulation of apoptotic signaling pathway | cell communication | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | humoral immune response | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | regulation of cytokine-mediated signaling pathway | positive regulation of B cell activation | lymphocyte activation | T cell differentiation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of organ growth | regulation of growth | response to organic substance | regulation of hemopoiesis | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | cell fate commitment | positive regulation of leukocyte activation | negative regulation of programmed cell death | receptor ligand activity | immune response | cytokine activity | animal organ development | regulation of cell activation | positive regulation of cytokine production | cell activation | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of developmental growth | regulation of cytokine production | anatomical structure morphogenesis | regulation of organ growth | regulation of developmental process | developmental process | regulation of chemokine production | regulation of B cell proliferation | regulation of cell-cell adhesion | immune system process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | negative regulation of cell death | positive regulation of leukocyte cell-cell adhesion | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

extracellular region | extracellular space