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QuickView for involucrin (gene)


Gene Symbol:
IVL Homo sapiens Homo sapiens
Full name:
involucrin
Synonyms:
involucrin
Genomic Location:
Chr 1: 151147663-151150986
Description:
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q21.3


Transcripts Names
NM_005547
XM_001130659
XM_003960264
Protein Names
Q5T7P4
P07476



GO Molecular Function

structural molecule activity | protein binding, bridging | molecular adaptor activity | protein binding

GO Biological Process

response to radiation | peptidyl-amino acid modification | cell differentiation | cellular process | tissue development | epithelium development | response to UV | cornification | response to stimulus | programmed cell death | protein modification process | peptide cross-linking | macromolecule modification | response to light stimulus | system development | nitrogen compound metabolic process | multicellular organism development | response to UV-B | epidermal cell differentiation | epidermis development | keratinization | skin development | keratinocyte differentiation | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine | protein metabolic process | anatomical structure development | metabolic process | peptidyl-lysine modification | organic substance metabolic process | cell death | animal organ development | cellular protein metabolic process | developmental process | cellular protein modification process | epithelial cell differentiation | cellular metabolic process | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | microtubule organizing center | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | centrosome | cornified envelope | nucleoplasm | plasma membrane | vesicle | extracellular exosome | microtubule cytoskeleton | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosol | cytoskeleton | intracellular | membrane