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for
k252a
(compound)
Summary
General Info
DrugBank
Identification
Name:
K 252a
Name (isomeric):
DB02152
Drug Type:
small molecule
Category:
Enzyme Inhibitors
CAS number:
97161-97-2
Targets
Hepatocyte growth factor receptor
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity
UniProt ID:
P08581
Gene:
MET
Actions:
unknown
References:
Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
View Article
Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.
View Article
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
View Article
Dual specificity mitogen-activated protein kinase kinase 1
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases
UniProt ID:
Q02750
Gene:
MAP2K1
Actions:
unknown
References:
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
View Article
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