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QuickView for kaolin (compound)


PubChem Substance
Name: Kaolin
PubChem Substance ID: 158192
Description: The most common mineral of a group of hydrated aluminum silicates, approximately H2Al2Si2O8-H2O. It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. (From Merck Index, 11th ed) The name is derived from Kao-ling (Chinese: "high ridge"), the original site. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Synonyms:
Argiflex; BOL Blanc; Burgess 10; Kaopectate; Apsilex; Amazon 88; White bole; Amazon Kaolin 855D; HSDB 630; CB 2 (clay).
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DrugBank
Identification
Name: Kaolin
Name (isomeric): DB01575
Drug Type: small molecule
Description: The most common mineral of a group of hydrated aluminum silicates, approximately H2Al2Si2O8-H2O. It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. (From Merck Index, 11th ed) The name is derived from Kao-ling (Chinese: "high ridge"), the original site. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Brand: Kaopectate
CAS number: 1332-58-7
Pharmacology
Indication: Used for upset stomach and diarrhea, a traditional medicine used in China, South America and Africa. Kaolin is also used to treat AIDs-related diarrhea. Kaolin based bandages are also under investigation.
Pharmacology: Kaolin is an adsorptive agent.
Mechanism of Action: Kaolin adsorbs water, toxins and bacteria, contributing to firmer stools, reducing fluid loss from diarrhea.
Interactions
Drug interaction:
PenciclovirThe multivalent agent decreases the effect of penicillamine
LincomycinThe aluminium salt decreases the absorption of lincosamides
ClindamycinThe aluminium salt decreases the absorption of lincosamides
ChloroquineThe antiacid decreases the absorption of chloroquine