QuickView for lamin B1 (gene)

Gene Symbol:

LMNB1 Homo sapiens

Full name:

lamin B1

Synonyms:

ADLD, LMN, LMN2, LMNB, lamin-B1

Genomic Location:

Chr 5: 126140732-126200608

Description:

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACGTG_MYC_Q2 ,  TTCNRGNNNNTTC_HSF_Q6 ,  GTACTGT_MIR101 ,  GCCATNTTG_YY1_Q6 ,  GGGAGGRR_MAZ_Q6 ,  YYCATTCAWW_UNKNOWN ,  ACTGAAA_MIR30A3P_MIR30E3P ,  NMYC_01 ,  CTTTGT_LEF1_Q2 ,  AAGCACA_MIR218

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-124u

miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes ,  hsa-miR-373 Targeted Genes

Cytogenetic Map:

5q23.2

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